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CD-1 Mouse Diet Pilot Study - Evaluations of Various Diets on Various Endpoints Critical to Evaluation of Bisphenol A (BPA) and Other Endocrine Active Agents in Mice.

Objective

<p>
<ol>
<li>Determine a diet for assessing the effect of endocrine active compounds, including BPA, on reproductive and metabolic parameters in CD-1 mice.</li>
<li>Evaluate the role of soy protein, with or without the ethanol extractable components of soy that include the isoflavones, in the effects of soy containing diets.</li>
<li>Conduct chemical and biological assays on the diets to determine the occurrence and variability of several component activities that could alter the in vivo response of the animal to such endocrine active compounds</li></ol></p>

More information

Responsible Division: Biochemical Toxicology

Investigators
Delclos, Kenneth
Institution
DHHS/FDA - National Center for Toxicological Research
DHHS/FDA - Center for Food Safety & Applied Nutrition
Project number
E0218301