An official website of the United States government.

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

Characterization of Plasmid-Associated Antimicrobial Resistance in Salmonella enterica Serovars Associated with Poultry and Human infections

Objective

<p>&nbsp;</p>

<ol>
<li>Identify and understand the genetic mechanisms associated with plasmids that facilitate the spread and persistence of virulence and multidrug in Salmonella from poultry-and-egg- associated serovars.</li>
<li>Sequence the plasmids from multidrug-resistant S. enterica serovar Enteritidis, Heidelberg, and Typhimurium strains to identify genes likely associated with virulence and antimicrobial resistance.</li>
<li>Determine the relative selective potential of antimicrobial agents to trigger the dissemination of antimicrobial resistance and virulence factors to susceptible Salmonella.</li>
<li>Determine the contribution of plasmids transferred via conjugation to virulence in Salmonella strains</li>
</ol>

<p>&nbsp;</p>

More information

Responsible Division: Microbiology

Investigators
Foley, Steven
Institution
DHHS/FDA - National Center for Toxicological Research
Start date
2010
End date
2011
Project number
E0733501