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Characterization of Plasmid-Associated Antimicrobial Resistance in Salmonella enterica Serovars Associated with Poultry and Human infections



<li>Identify and understand the genetic mechanisms associated with plasmids that facilitate the spread and persistence of virulence and multidrug in Salmonella from poultry-and-egg- associated serovars.</li>
<li>Sequence the plasmids from multidrug-resistant S. enterica serovar Enteritidis, Heidelberg, and Typhimurium strains to identify genes likely associated with virulence and antimicrobial resistance.</li>
<li>Determine the relative selective potential of antimicrobial agents to trigger the dissemination of antimicrobial resistance and virulence factors to susceptible Salmonella.</li>
<li>Determine the contribution of plasmids transferred via conjugation to virulence in Salmonella strains</li>


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Responsible Division: Microbiology

Foley, Steven
DHHS/FDA - National Center for Toxicological Research
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