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Detection of BSE Prions from Cattle and Sheep using Transgenic Mice and Conformation-Dependent Immunoassay


This research project aims to improve methods for the detection of BSE infection in cattle and sheep including differentiation between BSE and scrapie infection in sheep.

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The aim of this joint FSA/ Defra study is to further characterise two complementary methods for detection of and discrimination between BSE and scrapie prions.

<p>These two methods are bioassay using transgenic mice expressing bovine prion protein (Tg(BoPrP) and the in vitro Confirmation-Dependent Immunoassay (CDI).

<p>Find more about this project and other FSA food safety-related projects at the <a href="; target="_blank">Food Standards Agency Research webpage</a>.

University of California - San Francisco
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