To develop bacteriophage encapsulation methodology that is optimal for chicken gastrointestinal track and investigate its efficacy to control S. typhimurium DT 104 in broiler production in comparison to non-encapsulated phages.
Our specific objectives are:
<OL> <LI> To develop a well protected encapsulated phage (Felix O1, as a model) for targeted delivery to chick intestine by oral administration.
<LI>To validate the efficacy of encapsulated phage for control of Salmonella in experimental chicks in comparison with non-encapsulated phage.
To provide important information towards the feasibility of using bacteriophages as a control agent against food-borne pathogens in food animal production. It may result in commercially available phage products that benefit poultry industry. The reduction of food-borne pathogens in poultry products will reduce foods safety risks and increase consumer confidence in poultry products. The poultry industry will benefit through improvement of animal health and growth. <P> For more information, please visit the <a href="http://www.omafra.gov.on.ca/english/research/foodsafety/index.html" target="_blank">Ontario Ministry of Agriculture, Food & Rural Affairs (OMAFRA) Food Safety Research Program</a>.