Development of an Integrated Risk Model for Foodborne Zoonotic Parasites in Swine

Though previous studies have identified characteristics of high risk management
systems, medium and low risk systems have not been completely characterized. We will
identify those management systems and strategies that reduce or eliminate Toxoplasma
from swine herds on the farm, and develop a comprehensive risk model for the swine
industry. Though pork has been identified as a potential source of human infection
for Toxoplasma, recent studies suggest that chicken may also be a risk for human
transmission. We will analyze Toxoplasma prevalence in chickens raised in different
management systems and develop practical interventions for reducing risk of exposure.
<p>Until recently, differentiation of foodborne versus oocyst transmission of Toxoplasma
to humans was impossible. Identification of stage specific antigens from oocysts
have made the development of a validated serological assay possible. We will use
these antigens to develop diagnostic methods to determine the most common
transmission route of Toxoplasma in humans.
<p>The U.S. export market for pork and horsemeat is dependent upon industry compliance
with the testing requirements of importing countries. The need for international
validation, standardization, and other quality control requirements for digestion-
based Trichinella testing is critical as countries compete for export markets. We
will collaborate with trading partners and international food safety organizations to
harmonize testing procedures for Trichinella in meat products destined for export.