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Fda Fern Cooperative Agreement Program


FDA FERN Cooperative Agreement ProgramCA Animal Health & Food Safety Laboratory SystemProject Summary/AbstractThe objective of this proposal is to continue our laboratory's involvement win the FERN CAP.This will enable us to continue with the analyses of foods and food products in the event that thereis a chemical food contamination incident that potentially compromises the safety of our nation'sfood supply. We will be participating, as needed, in the development, validation and expansion ofmethods designed to screen a variety of food matrices for diverse and potentially harmfulchemicals including unknown compounds, using GC/MS, LC/MS, ICP/MS and ELISAmethodologies. We will be participating in surveillance assignments enacted by the FDA.Laboratory personnel will participate in training exercises designed to assess the ability of FERNto respond to various contamination scenarios, participate in national and regional trainingconferences, and assist in the validation and expansion of existing FERN methods. The laboratorywill pursue ISO-17025 accreditation. Our quality program will be tested via our participation inFERN proficiency exercises.Specifically, the objectives that will be met include: ? Revalidate method TO-22 on the VELOS platform. ? Validate method TO-22 on the Q-Exactive platform. ? Validate method CHE.006 on the Agilent 7890 GC-MS utilizing DRS software. ? Validate Saxitoxin ELISA screen on food matrices. ? Develop and validate a multi-analyte mycotoxin screen on grains and feeds. ? Develop and validate the speciated arsenic method on seaweed, apple juice and rice. ? Develop and validate a method for the analysis of zinc phosphide on infant formula and animal feed. ? Participate in proficiency testing of current food testing methodologies. ? Participate in method enhancement activities to extend analytical capacity. ? Participate in the analysis of surveillance samples. ? Participate in the analysis of emergency outbreak samples. ? Achieve ISO 17025 accreditation. ? Participate in national and regional FERN training opportunities. ? Effectively communicate with other FERN laboratories and the FERN NPO.

Poppenga , Robert
University of California - Davis
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