An official website of the United States government.

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

Investigating the Mechanisms of Drug Resistance and Pathogenicity in Clinical Escherichia Coli Isolates from Veterinary Sources

Objective

<P>
<ol>
<li>Evaluate the antimicrobial susceptibility profiles in E. coli and detect the prevalence of antimicrobial-resistance genes for the resistant phenotypes.</li>
<li>Investigate the mutational changes in gyrase and regulatory genes, and assess the role of plasmids and integrons in mediating the drug resistance.</li>
<li>Characterize the molecular basis of drug resistance in E. coli displaying extended-spectrum beta-lactamase phenotypes.</li>
<li>Evaluate the virulence gene profiles of the isolates</li></ol></p>

More information

Responsible Division: Microbiology

Investigators
Nayak, Rajesh
Institution
DHHS/FDA/CVM - Division of Animal and Food Microbiology
DHHS/FDA - National Center for Toxicological Research
Project number
E0744901