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Managing the Emerging Risk of Trichinellosis in Organic and Free Range Pork

Objective

1. Develop serological assays that differentiate swine chronically infected with zoonotic T. spiralis from swine only transiently exposed to T. murrelli.

2. Estimate how frequently pastured pigs and feral swine are exposed to infection with enzootic and zoonotic species of trichinella.

More information

Approach:
Screen expression libraries of T. spiralis and T. murrelli with hyper-immune sera from swine to identify clones encoding species-specific diagnostic antigens. Develop antibodies that discriminate among the two types of infection. Test in experimentally infected swine. Apply to panels of serum collected from feral swine and pastured pigs. Validate against genotyped parasite specimens obtained from tissue samples matched with serum.

Investigators
Rosenthal, Benjamin
Institution
USDA - Agricultural Research Service
Start date
2011
End date
2015
Project number
8042-42000-016-01-R
Accession number
421221
Categories
Commodities