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National Agricultural Library
U.S. Department of Agriculture
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Prion Infection of Tongue

Objective

To determine the cellular and subcellular sites of replication of scrapie agent in the tongue of sheep.

More information

APPROACH: Experimentally expose sheep to scrapie. Collect tongue tissues from scrapie-exposed sheep. Determine cellular localization of the scrapie agent in the tongue in order to ascertain its distribution in the lymphoreticular and nervous systems as well as in skeletal muscle and taste cells.

Investigators
Hamir, Amirali ; Bessen, Richard; Richt, Jürgen
Institution
USDA - Agricultural Research Service
Start date
2005
End date
2008
Funding Source
Nat'l. Inst. of Food and Agriculture
Project number
3625-32000-073-14R
Accession number
411092
Categories
Viruses and Prions
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