Prion Infection of Tongue | National Agricultural Library

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National Agricultural Library

U.S. Department of Agriculture

Objective

To determine the cellular and subcellular sites of replication of scrapie agent in the tongue of sheep.

More information

APPROACH: Experimentally expose sheep to scrapie. Collect tongue tissues from scrapie-exposed sheep. Determine cellular localization of the scrapie agent in the tongue in order to ascertain its distribution in the lymphoreticular and nervous systems as well as in skeletal muscle and taste cells.

Investigators

Hamir, Amirali ; Bessen, Richard; Richt, Jürgen

Institution

USDA - Agricultural Research Service

Start date

2005

End date

2008

Funding Source

Nat'l. Inst. of Food and Agriculture

Project number

3625-32000-073-14R

Accession number

411092