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Risk Assessment (General)


Efforts in the improvement of Risk Assessment.

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FY 2000 Accomplishments: 1) Continued to work on change-point dose-response models for continuous data. 2) Continued to work on dose-response models for clustered exchangeable binary data. 3) Completed work on combining uncertainty factors when setting exposure levels.Presented talk at FDA Science Forum and had one paper published. 4) Initiated work on risk-based Rank Fish Detector (RFD). 5) Submitted manuscript for publication. 6) Continued work on method for body-weight-adjusted analysis of tumor data.Submitted manuscript for publication. 7) Finalized work on dose-response modeling for mixed populations and fordevelopmental neurotoxicity. 8) Two papers published.
FY 2001 Plans: Continue risk assessment research efforts.

Kodell, Ralph
DHHS/FDA - National Center for Toxicological Research
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