Objective 1: Develop practical, systems-based strategies, for management of pests of fresh fruit and high valuable durable commodities (e.g., navel orangeworm in almonds, pistachios and walnuts, mealybugs on table grapes, codling moth in walnuts, tephritid fruit flies in fruit) through all aspects of production, distribution, and marketing that enhance production and commodity quality. Subobjective 1A: Characterize the biotic and abiotic factors that affect the insecticides used to control navel orangeworm in tree nuts in order to optimize their efficacy and minimize non-target impacts on human health and environmental quality. Subobjective 1B: Characterize and optimize semiochemical strategies for monitoring and control of key dipteran and lepidopteran pests in the context of minimizing preharvest and post-harvest chemical treatment requirements. Subobjective 1C: Characterize and optimize biocontrol strategies for key lepidopteran and dipteran pests in the context of minimizing preharvest and post-harvest chemical treatment requirements. Subobjective 1D: Develop an overall metric of treatment efficacy, via combining the individual contributions from preharvest and post-harvest processes, to evaluate systems-based strategies for insect control in fresh and durable commodities. Objective 2: Develop new treatment technologies or modify existing protocols for post-harvest treatment of pests, such as the Indianmeal moth and the red flour beetle, with the objective of minimizing negative effects to the environment and food quality, while maintaining the positive sensory qualities and marketability of these commodities. Subobjective 2A: Develop technologies to reduce, or eliminate, atmospheric emissions from ventilation effluent following post-harvest fumigations. Subobjective 2B: Develop treatments for novel post-harvest applications involving fresh and durable commodities. Subobjective 2C: Improve semiochemical-based strategies for controlling stored product insect pests in post-harvest scenarios. Objective 3: Develop treatment technologies for action agencies that require alternatives to methyl bromide for phytosanitary and quarantine treatment of pests such as the codling moth, spotted wing drosophila, and Fuller rose beetle. Conduct research to support USDA-APHIS negotiations with trade partners as well as research on the fate and transport of post-harvest agrochemicals, thereby enhancing the competitiveness of U.S. agriculture in the global marketplace. Subobjective 3A: Develop post-harvest treatments for quarantine purposes that minimize reliance on post-harvest methyl bromide (MeBr) fumigations. Subobjective 3B: Obtain sorption and depuration data related to post-harvest fumigations to serve as physicochemical basis for regulation related to nontarget human ingestion and inhalation exposures. Subobjective 3C: Identify agrochemical use strategies and novel technologies to ensure foodstuff residues are compliant with importer regulations.