The MANDALA project presents a sustainable solution for the plastic packaging sector which tackles 3 pillars: eco-design, dual functionality & end-of-life; with the aim to find a final solution based on multilayer monomaterial packaging with functionalities compared to multimaterial ones and fully produced with biobased & recycled polymers in order to reach a full circularity of resources. MANDALA will develop new adhesives with dual functionality (easy to split and barrier properties) by incorporating thermoreversible covalent bonds and radiation absorbing nanoparticles, which at the same time will generate a tortuous path enhancing barrier properties that are critical for end-user. In addition, new polymer blends with increased biobased and recycled content of film layers will be developed. Their combination in a multilayer product will set the basis for new food (meat, ready-to-eat) and pharma (pill blister) packaging products. MANDALA project will demonstrate that the de-lamination technology can be up-scaled and applied to reach intermediate solutions for multilayer/multimaterial packaging (being biobased or not) progressively helping to become the end-of-life more sustainable by recovering all fractions and providing clean streams for their biodegradation or recycling. MANDALA project will directly contribute to achieve KPI 1, KPI 2, KPI 6, KPI 8 and demonstrate the solution decreasing the end-of-life costs and CO2 emissions in more than a 30%. It will develop innovations in 3 KETS. MANDALA consortium involves 12 partners (4RTD, 5SME, 1SME cluster and 2 Large Companies) accounting 2 BIC full members and 2 associated. The 42-months project will comprise a total estimated budget of 4,573,892,5€ and requested funding of 3,650,921,75€. There is a strong engagement of the industry with 922,970,75€ in-kinds (20,2%) and 4,869,731€ in additional activities during the project (machine acquisition) and 3,820,000€ envisaged to upgrade TRL after the end of the project.