The following videos are selected presentations focusing on 3Rs (replacement, reduction, and refinement of animal use) methods to improve laboratory animal welfare while maintaining or improving scientific results. Topics include liver-chip technologies, environmental health monitoring, refinement and enrichment strategies, regulatory insights into the 3Rs among other topics. The 2023 Symposium playlist on The 3Rs in Action! can be viewed on YouTube or as individual videos below.
The 2023 Symposium was held virtually and co-hosted by:
- USDA, NAL, Animal Welfare Information Center (AWIC)
- NIH Office of Laboratory Animal Welfare (OLAW)
- Johns Hopkins Department of Molecular and Comparative Pathobiology
- Johns Hopkins Center for Alternatives to Animal Testing (CAAT)
Organizers’ Welcome: 10th Anniversary
Speakers: Patricia Brown, NIH, OLAW; Eric Hutchinson, Johns Hopkins Department of Molecular and Comparative Pathobiology; Joanne Zurlo, Kathrin Herrmann, Johns Hopkins CAAT; and Kristina Adams, USDA, AWIC
Keynote Orphan 3Rs
Speaker: Thomas Hartung, Johns Hopkins Center for Alternatives to Animal Testing (CAAT)
Welfare of Primates in Laboratories: Opportunities for Refinement
Speaker: Hannah Buchanan-Smith, University of Stirling
Arguments Against Nonhuman Primate Research, & Why Replacement Must Be the Focus
Speaker: Jarrod Bailey, Animal Free Research U.K.
How Do We Effectuate the 3Rs?
Speaker: Merel Ritskes-Hoitinga, Utrecht University
Performance Assessment of a Liver-Chip for Prediction of Drug-Induced Liver Injury and Incorporation Within Laboratory Workflows
Speaker: Lorna Ewart, Emulate
Replacing Sentinel Rodents With Environmental Health Monitoring
Speaker: Megan Lafollette, 3Rs Collaborative, Inc.
Practical Implementation of Enrichment for Laboratory Zebrafish
Speaker: Chloe Stevens, Royal Society for the Prevention of Cruelty to Animals (RSPCA)
Refinements in Cage Bedding for the Improvement of Mouse Welfare and Husbandry Efficiency
Speaker: Brooke Pallas, University of Michigan
Practical Application of Cumulative Endpoints
Speaker: Pat Turner, Charles River Laboratories
Pathways to Continuous Improvement
Speaker: Steve Niemi, Boston University
Panel Discussion with AAALAC/FDA/NIH/USDA on the 3Rs
Speakers: Gary Borkowski, AAALAC International; Suzanne Fitzpatrick, FDA; Nicolette Petervary, NIH OLAW; Gwen Maginnis, USDA APHIS AC
These presentations are being hosted by the Animal Welfare Information Center, a service of The National Agricultural Library. Staff did not edit or otherwise modify the original materials. The views expressed in the presentations do not necessarily reflect the policies of the National Agricultural Library or the United States Department of Agriculture.