BREAKTHROUGH POSTBIOTIC TREATMENT TO REDUCE PATHOGEN LOAD IN BROILERS WHILE IMPROVING FEED EFFICIENCY

Goal 1: Demonstrate that FPZ can be an effective feed additive in poultryObjective 1. Carry out an in vivo poultry trial to demonstrate that orally administered FPZ can be used as an effective feed additive in poultry by providing benefit in either or both of the following:A) Reducing levels of the important bacterial pathogens Salmonella enteritidis to prevent downstream human infections.B) Reducing broiler chicken production costs by improving feed efficiency.Goal 2: Determine the mechanism by which FPZ improves feed efficiency and reduces pathogen-load in poultryObjective 2. Use cell-based assays in multiple poultry cell lines, as well as other in vitro assays to assess the mechanism by which FPZ is leading to improvements in feed efficiency and pathogen-load reduction in poultry.