This project aims to increase the efficacy of burbot (Lota lota) commercial aquaculture, with theultimate goal of establishing a commercial burbot production hatchery to supply burbot to the USmarket. To increase efficacy of commercial burbot aquaculture, three objectives are proposed:1. Development and evaluation of a vaccine to reduce mortality from bacterial pathogens infingerling and juvenile burbot.2. Investigation of parameters that may cause swim bladder overinflation related mortality inlarval burbot.3. Determination of conditions that result in reliable and consistent tetraploid burbot production.