Enhancement of California's Integrated Food Safety and Security System

Proposed Application: Enhancement of California?s Integrated Food Safety and Security SystemThe Food and Drug Laboratory Branch (FDLB), California Department of Public Health (CDPH) issubmitting the following proposal for FOA# PAR-20-105, under disciplines of Microbiology (A), Chemistry(B), and discipline D Special Projects. FDLB has been an FDA FERN laboratory since 2008. FDLB has thecapability and capacity to fulfill the goals of the referenced cooperative agreement program in terms ofthe experience and expertise of its trained staff, available facilities, established validated equipment,and its on-going participation in FERN training, surveillance, proficiency testing, and other cooperativeagreement programs activities. FDLB is the primary testing laboratory for State food and drug regulatoryagency which enrolled in California?s Manufactured Food Regulatory Program Standards.1. Three projects in Chemistry area (PI: Dr. Dadong Xu, Dadong.Xu@cdph.ca.gov):(1) Discipline B Track 1, Food Defense (150 samples): We are proficient in all three FERN chemistrymethods (CHE.0006, CHE.0008, and EAM 4.7) as well as FDLB-developed methods to carry out the tasksfor this track, with capacity of more than 150 samples; 2) Discipline B Track 2, Human Food ProductTesting (500 samples): We have the capability and capacity to perform human food product testing for avariety of analytes, such as natural toxins, toxic metals, seafood toxins, and some pesticides. We will beable to enhance our testing capability in additional analytes including vitamins and drug residues; 3)Discipline D Special Projects, Track 3, Method Development / Validation in Chemistry: We apply toparticipate in all the single and multi-laboratory validations for histamine, arsenic speciation in seafood,bottled water analysis using ICP-MS, and veterinary drug residues in milk products.2. Eight Projects in Microbiology area (PI: Dr. David Kiang, David.Kiang@cdph.ca.gov):Discipline A track (1) Food Defense- We have the capacity to analyze all the proposed food and foodproducts related to microbiological contamination through intentional means and to enhance thenetwork capacity and readiness of state BLS2+ and BSL3 laboratories; track (2) Human Food ProductTesting- We can improve the food testing surveillance programs through microbiological analysis offood products and environmental samples; track (3) Animal Food Product Test- We can analyze animalfood products for microbiological contaminants and improve the animal food testing surveillanceprogram for the state; Track (4) Whole Genome Sequencing; track ( 5) Microbiology Capability/Capacitydevelopment 2020-21; Discipline D Special Projects, track (1) Sample collection for microbiology andChemistry; track (2) NFSDX and ORAPP integration; track (3) Method Development/Validation formicrobiology - We will participate in the two multi-lab validations.