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National Agricultural Library
U.S. Department of Agriculture
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  4. Impact of Transformation Methods, Construct and Gene Cassette Architecture on the Stability and Expression of Transgenes

Impact of Transformation Methods, Construct and Gene Cassette Architecture on the Stability and Expression of Transgenes

Objective

This project is aimed at understanding the relationships between the method of transgenic DNA delivery into the plant DNA structure, construct architecture and gene architecture on the expression of individual transgenes in barley and wheat.

More information

The research will investigate whether transgene recombination prior to integration plays a role in transgene instability in the bacterial hosts and the effect of insertion of unwanted sequences.

<p>This project will also address the question as to whether scaffold attachment region (SAR) elements can increase and stabilise gene expression and whether introns play an important role as suppressers of position effects.

<p>Find more about this project and other FSA food safety-related projects at the <a href="http://www.food.gov.uk/science/research/&quot; target="_blank">Food Standards Agency Research webpage</a>.

Institution
John Innes Centre, Norwich, UK
Start date
1998
End date
2001
Funding Source
Food Standards Agency
Project number
G01009