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A Mixture Model Approach to Classifying CYP1A2 Variants that Adjusts for their Current Smoking Status


To examine statistical methods for parametric density estimation based upon a mixture of normal distributions; To apply the method to a data set where hepatic cytochrome P4501A2 activity appears to be induced by smoking cigarettes.

Delongchamp, Robert
DHHS/FDA - National Center for Toxicological Research
Project number