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Reducing antimicrobial resistance dissemination in broiler chickens using phytochemicals


This project aims to mitigate antimcirobial resistance (AMR) in the poultry production continuum using in-feed supplementation of phytochemcials in poultry feed. Specifically, the objectives of this proposal are (1) To investigate the effect of select phytochemicals on horizontal gene transfer of β-lactamase gene (blaTEM) from MDR S. Heidelberg to commensal bacteria in the chicken gut (2)To develop and apply Hi-C sequencing and metagenomics foranalyzingthepersistence and extent of spread of AMR genetic elements in the cecal gut microbiota of broilers that are supplemented with the select phytochemicals.

Pellissery, A.
University of Connecticut
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