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Research Publications (Food Safety)

This page tracks research articles published in national and international peer-reviewed journals. Recent articles are available ahead of print and searchable by Journal, Article Title, and Category. Research publications are tracked across six categories: Bacterial Pathogens, Chemical Contaminants, Natural Toxins, Parasites, Produce Safety, and Viruses. Articles produced by USDA Grant Funding Agencies (requires login) and FDA Grant Funding Agencies (requires login) are also tracked in Scopus.

Displaying 476 - 500 of 2000

  1. Metabolomic Analysis Reveals the Mechanisms of Hepatotoxicity Induced by Aflatoxin M1 and Ochratoxin A

    • Toxins
    • Aflatoxin M1 (AFM1) is the only toxin with the maximum residue limit in milk, and ochratoxin A (OTA) represents a common toxin in cereals foods. It is common to find the co-occurrence of these two toxins in the environment. However, the interactive effect of these toxins on hepatoxicity and underlying mechanisms is still unclear.

      • Natural toxins
      • Aflatoxins
      • Mycotoxins
  2. Food-Grade Expression of Manganese Peroxidases in Recombinant Kluyveromyces lactis and Degradation of Aflatoxin B1 Using Fermentation Supernatants

    • Frontiers in Microbiology
    • Aflatoxins are naturally occurring high-toxic secondary metabolites, which cause worldwide environmental contaminations and wastes of food and feed resources and severely threaten human health. Thus, the highly efficient methods and technologies for detoxification of aflatoxins are urgently needed in a long term.

      • Natural toxins
      • Aflatoxins
      • Mycotoxins
  3. Hollow-Structured Microporous Organic Networks Adsorbents Enabled Specific and Sensitive Identification and Determination of Aflatoxins

    • Toxins
    • Aflatoxin (AFT) contamination, commonly in foods and grains with extremely low content while high toxicity, has caused serious economic and health problems worldwide. Now researchers are making an effort to develop nanomaterials with remarkable adsorption capacity for the identification, determination and regulation of AFT. Herein, we constructed a novel hollow-structured microporous organic networks (HMONs) material.

      • Natural toxins
      • Aflatoxins
      • Mycotoxins
  4. Efficacy of Cinnamomum camphora essential oil loaded chitosan nanoemulsion coating against fungal association, aflatoxin B1 contamination and storage quality deterioration of Citrus aurantifolia fruits

    • International Journal of Food Science & Technology
    • International Journal of Food Science & Technology, EarlyView. The present study demonstrates the first time investigation on Cinnamomum camphora essential oil (CCEO) loaded chitosan nanoemulsion coating on Citrus aurantifolia fruits to ensure protection against Aspergillus flavus infestation and aflatoxin B1 (AFB1) contamination.

      • Natural toxins
      • Aflatoxins
      • Mycotoxins
  5. An ultralow concentration of Al-MOFs for turn-on fluorescence detection of aflatoxin B1 in tea samples

    • Food Chemistry
    • A turn-on fluorescent sensing platform based on an ultralow concentration of Al-metal organic frameworks for the detection of aflatoxin B1 has been developed for the first time. This fluorescence turn-on sensor exhibits the largest fluorescence enhancement (or quenching) constant value of 179404 M-1 among all luminescence-based chemical sensors reported till date.

      • Natural toxins
      • Aflatoxins
      • Mycotoxins
  6. Fish feed mycobiota and aflatoxins in round fish tissues

    • Journal of the Science of Food and Agriculture
    • Journal of the Science of Food and Agriculture, Volume 102, Issue 4, Page 1391-1396, 15 March 2022. Round fish is one of the most consumed fish in Brazil. Farmed fish feed is based mainly on grains, which are susceptible to contamination by mold and mycotoxins. Aspergillus spp., Penicillium spp. and Fusarium spp. are the major mycotoxins producers.

      • Natural toxins
      • Aflatoxins
      • Mycotoxins
  7. Aflatoxin B1 in rice: effects of storage duration, grain type and size, production site and season

    • Our study aimed to evaluate the AFB1 levels in packed rice marketed in Lebanon and determine the exposure to this toxin from the rice consumption. A total of 105 packed white, parboiled and brown rice bags were collected. ELISA was used to measure AFB1. A comprehensive FFQ was filled by 500 participants to determine the patterns of rice consumption and subsequently the exposure levels to AFB1 from the rice consumption in Lebanon. AFB1 was detected in all rice samples (100%).

      • Natural toxins
      • Aflatoxins
      • Mycotoxins
  8. Two-year survey of aflatoxin M1 in milk marketed in Albania, and human exposure assessment

    • Food Control
    • Aflatoxin M1 (AFM1), a metabolite of aflatoxin B1 (AFB1), is detected in milk obtained from ruminants fed AFB1-contaminated feedstuff. Considering the potential risk of aflatoxin exposure for human health, the AFM1 content in milk and dairy products is regularly monitored. A survey on AFM1 contamination in milk from retail markets consumed in Albania was conducted in 2019–2020.

      • Natural toxins
      • Aflatoxins
      • Mycotoxins
  9. Analysis of Mycotoxin and Secondary Metabolites in Commercial and Traditional Slovak Cheese Samples

    • Toxins
    • Cheese represents a dairy product extremely inclined to fungal growth and mycotoxin production. The growth of fungi belonging to Aspergillus, Penicillium, Fusarium, Claviceps, Alternaria, and Trichoderma genera in or on cheese leads to undesirable changes able to affect the quality of the final products. In the present investigation, a total of 68 types of commercial and traditional Slovak cheeses were analyzed to investigate the occurrence of fungal metabolites.

      • Natural toxins
      • Aflatoxins
      • Mycotoxins
  10. Aspergillus flavus La3279, a component strain of the Aflasafe™ biocontrol product, contains a partial aflatoxin biosynthesis gene cluster followed by a genomic region highly variable among A. flavus isolates

    • International Journal of Food Microbiology
    • Aspergillus flavus communities in agricultural fields consist of isolates with varying abilities to produce aflatoxins, which are highly toxic and carcinogenic to humans and animals. Biological control using multiple non-aflatoxigenic strains as a formulation to outcompete aflatoxigenic A. flavus has become a mainstream strategy. Aflasafe™ is a biocontrol product composed of four strains, Ka16127, La3279, La3304 and Og0222.

      • Natural toxins
      • Aflatoxins
      • Mycotoxins
  11. Improvements within the peanut production chain to minimize aflatoxins contamination: An Ethiopian case study

    • Food Control
    • Peanuts (Arachis hypogaea L.) are a worldwide crop appreciated by consumers and known to have several health benefits (e.g. decreasing risk of cardiovascular diseases, lowering LDL cholesterol). Nonetheless, during the production chain, peanuts can be contaminated by mycotoxigenic fungi, especially Aspergillus flavus and A. parasiticus, responsible for contamination of this commodity with aflatoxins (AFs).

      • Natural toxins
      • Aflatoxins
      • Mycotoxins
  12. Aflatoxin B1 causes oxidative stress and apoptosis in sheep testes associated with disrupting rumen microbiota

    • Ecotoxicology and Environmental Safety
    • Aflatoxin B1 (AFB1) is an unavoidable environmental pollutant commonly found in feed and foodstuffs. It is the most toxic one of all the aflatoxins, which can cause severe impairment to testicular development and function. Yet, the underlying mechanisms of reproductive toxicity in rams sheep remain inconclusive. The study was designed to explore the effects of AFB1 on sheep testes through rumen-microbiota, oxidative stress and apoptosis.

      • Natural toxins
      • Aflatoxins
      • Mycotoxins
  13. A Dilute-and-Shoot UHPLC–MS/MS Isotope Dilution Method for Simultaneous Determination and Confirmation of 11 Mycotoxins in Dried Distiller’s Grains with Solubles

    • Journal of AOAC INTERNATIONAL
    • Background Natural contamination with mycotoxins in dried distiller’s grains with solubles (DDGS) as a mainstream animal feed ingredient poses a risk to animal health. Objective A regulatory method was needed for the agency to simultaneously detect 11 mycotoxins of high regulatory priority in DDGS. Methods A DDGS sample (10 g) was extracted twice with acetonitrile-water under mildly acidic condition.

      • Natural toxins
      • Aflatoxins
      • Mycotoxins
  14. An HPLC-MS/MS Method Using a Multitoxin Clean up Column for Analysis of Seven Mycotoxins in Aquafeeds

    • Journal of AOAC INTERNATIONAL
    • Background In Guangdong Province of China, the climate is very wet, so there are many different fungi living in aquatic feeds, which produce mycotoxins. These compounds contaminate agricultural products worldwide and present a great threat to human health. It is necessary to determine their contamination level in aquatic feeds.

      • Natural toxins
      • Aflatoxins
      • Mycotoxins
  15. Characterization of 260 Isolates of Aspergillus Section Flavi Obtained from Sesame Seeds in Punjab, Pakistan

    • Toxins
    • Sesame Sesamum indicum L. is a major oil-based seed crop that has been widely cultivated and consumed in Pakistan. Unfortunately, sesame is highly prone to Aspergillus fungal growth in the field, and under inappropriate storage conditions can become contaminated with aflatoxins, the most potent carcinogen found in nature.

      • Natural toxins
      • Aflatoxins
      • Mycotoxins
  16. How do Time, Tannin and Moisture Content Influence on Toxicogenic Fungal Populations during the Storage of Sorghum Grains?

    • Cereal grains are usually ensiled to improve their nutritional value and are one of the main sources of feed for dairy cattle. However, during storage, grains can be contaminated with toxicogenic fungi. Sorghum is one of the most economically important cereals in the world. Therefore, the aim of this work was to evaluate the influence of storage duration and tannin and moisture contents on toxicogenic fungal populations in sorghum grain storage.

      • Natural toxins
      • Aflatoxins
      • Mycotoxins
  17. Spatio-Temporal Patterns of Aspergillus Flavus Infection and Aflatoxin B1 Biosynthesis on Maize Kernels Probed by SWIR Hyperspectral Imaging and Synchrotron FTIR Microspectroscopy

    • Food Chemistry
    • The dynamics mechanisms regulating the growth and AFB1 production of Aspergillus flavus during its interactions with maize kernels remain unclear. In this study, shortwave infrared hyperspectral imaging (SWIR-HSI) and synchrotron radiation Fourier transform infrared (SR-FTIR) microspectroscopy were combined to investigate chemical and spatial-temporal changes in incremental damaged maize kernels induced by A.

      • Natural toxins
      • Aflatoxins
      • Mycotoxins
  18. A Systematic Review of the Efficacy of Interventions to Control Aflatoxins in the Dairy Production Chain—Feed Production and Animal Feeding Interventions

    • Toxins
    • The study presents a systematic review of published scientific articles investigating the effects of interventions aiming at aflatoxin reduction at the feed production and animal feeding phases of the milk value chain in order to identify the recent scientific trends and summarize the main findings available in the literature. The review strategy was designed based on the guidance of the systematic review and knowledge synthesis methodology that is applicable in the field of food safety.

      • Natural toxins
      • Aflatoxins
      • Mycotoxins
  19. Mycotoxins binder supplementation alleviates aflatoxin B1 toxic effects on the immune response and intestinal barrier function in broilers

    • Poultry Science
    • This experiment was conducted to evaluate whether a commercial mycotoxins-binder, XL, could effectively attenuate the negative effects of Aflatoxin B1 (AFB1) on growth performance, immunological function, and intestinal health in birds.

      • Natural toxins
      • Aflatoxins
      • Mycotoxins
  20. Early expression of the aflatoxin gene cluster in Aspergillus nomiae isolated from Brazil nut

    • Toxicon
    • Aspergillus nomiae is the most important contaminant in Brazil nut due to its high incidence in these nuts and its strong production of carcinogenic metabolites: aflatoxins (AF). Aflatoxin biosynthesis pathway in A. nomiae is poorly studied. Thus, in present investigation, aflatoxin production and gene cluster (aflCaflQaflU, and aflX) expression profile were evaluated on two strains of A.

      • Natural toxins
      • Aflatoxins
      • Mycotoxins
  21. Simultaneous distribution of aflatoxins B1 and B2, and fumonisin B1 in corn fractions during dry and wet-milling

    • Journal of Food Science and Technology
    • One of the limitations of the use of corn in the food chain is its contamination with mycotoxins. Reduction in their levels can be achieved by processing the grain, which in the case of corn can be achieved by wet or dry milling. The aim of this study was to compare the distribution of aflatoxins B1 and B2, and fumonisin B1 in corn fractions obtained by dry and wet milling, aiming to identify conditions to mitigate the risk of exposure to these contaminants.

      • Natural toxins
      • Aflatoxins
      • Mycotoxins
  22. Spent Coffee Grounds Valorization as Bioactive Phenolic Source Acquired Antifungal, Anti-Mycotoxigenic, and Anti-Cytotoxic Activities

    • Toxins
    • Spent coffee grounds (SCGs), which constitute 75% of original coffee beans, represent an integral part of sustainability. Contamination by toxigenic fungi and their mycotoxins is a hazard that threatens food production. This investigation aimed to examine SCGs extract as antimycotic and anti-ochratoxigenic material. The SCGs were extracted in an eco-friendly way using isopropanol. Bioactive molecules of the extract were determined using the UPLC apparatus.

      • Natural toxins
      • Aflatoxins
      • Mycotoxins
  23. Self-enhanced electrochemiluminescence of luminol induced by palladium–graphene oxide for ultrasensitive detection of aflatoxin B1 in food samples

    • Food Chemistry
    • In this work, a novel and credible electrochemiluminescence immunoassay (ECLIA) was constructed for the ultrasensitive and highly selective detection of aflatoxin B1 (AFB1). Amino-functionalized 3D graphene hydrogel (NGH) served as the ECL platform with the self-enhanced ECL of luminol–palladium–graphene oxide (lum–Pd–GO) acting as a marker for the antibodies against AFB1.

      • Natural toxins
      • Aflatoxins
      • Mycotoxins
  24. Fungal diversity and occurrence of Aflatoxin B1, Citrinine and Ochratoxin A in rice of Cameroon

    • Journal of Food Processing and Preservation
    • Journal of Food Processing and Preservation, Accepted Article. Rice is an important cereal for Cameroon where 95% of the population consumes it frequently. In order to ensuring a healthy food supply to consumers, the objective of this study was to determine the fungal profile and quantify mycotoxins in twelve rice samples produced in Cameroon.

      • Natural toxins
      • Aflatoxins
      • Mycotoxins
  25. Invited review: Remediation strategies for mycotoxin control in feed

    • Journal of Animal Science and Biotechnology
    • Mycotoxins are secondary metabolites of different species of fungi. Aflatoxin B1 (AFB1), deoxynivalenol (DON), zearalenone (ZEN) and fumonisin B1 (FB1) are the main mycotoxins contaminating animal feedstuffs. These mycotoxins can primarily induce hepatotoxicity, immunotoxicity, neurotoxicity and nephrotoxicity, consequently cause adverse effects on the health and performance of animals.

      • Natural toxins
      • Aflatoxins
      • Mycotoxins