An official website of the United States government.

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

Research Publications (Food Safety)

This page tracks research articles published in national and international peer-reviewed journals. Recent articles are available ahead of print and searchable by Journal, Article Title, and Category. Research publications are tracked across six categories: Bacterial Pathogens, Chemical Contaminants, Natural Toxins, Parasites, Produce Safety, and Viruses. Articles produced by USDA Grant Funding Agencies (requires login) and FDA Grant Funding Agencies (requires login) are also tracked in Scopus.

Displaying 1 - 25 of 33

  1. Aflatoxin levels in poultry feed: A comparison of mash and pellet forms

    • Poultry Science
    • The current research was conducted to determine and frequency of aflatoxins (B1, B2, G1, G2), in main feed ingredients (corn and soybean meal) and poultry finished feed (in mash and pellet forms). Eighty-five samples of corn, soybean meal, and poultry finished feed was randomly collected from feed mills in Iran.

      • Natural toxins
      • Aflatoxins
      • Mycotoxins
  2. Research Note: Effects of feeding corn naturally contaminated with aflatoxin B1, deoxynivalenol, and zearalenone on reproductive performance of broiler breeders and growth performance of their progeny chicks

    • Poultry Science
    • To evaluate the toxic effects of mycotoxin-contaminated corn (MC) on the breeders and their progeny chicks, a total of 480 fifty-wk-old Cobb broiler breeder hens were fed the following dies: 1) a corn-soybean meal diet (Control; containing 70.35% corn), 2) MC substituting for 5

      • Natural toxins
      • Aflatoxins
      • Mycotoxins
  3. Response surface model to illustrate the benefits of tryptophan, melatonin, and N,N-dimethylglycine in quail chicks exposed to aflatoxin B1

    • Poultry Science
    • A dose-response assay in a central composite design platform was conducted to investigate the responses (performance, immunity, and meat quality) of quail chicks to dietary tryptophan (Trp), melatonin (MEL), and N,N-dimethylglycine (DMG) exposed to aflatoxin B1&nbsp

      • Natural toxins
      • Aflatoxins
      • Mycotoxins
  4. Effects of supplemented multicomponent mycotoxin detoxifying agent in laying hens fed aflatoxin B1 and T2-toxin contaminated feeds

    • Poultry Science
    • The present study was conducted to determine the ability of multicomponent mycotoxin detoxifying agent (MMDA) in feed to prevent the gastrointestinal absorption of aflatoxin B1 (AFB1) and T2-toxin supplemented via spiked maize.

      • Natural toxins
      • Aflatoxins
      • Mycotoxins
  5. A consortium of detoxifying bacteria mitigates the aflatoxin B1 toxicosis on performance, health, and blood constituents of laying hens

    • Poultry Science
    • Detoxification approaches are evolving from physical to biological to eliminate the toxins altogether. The current study was conducted to compare the impact of 2 newly developed toxin deactivators, Magnotox-alphaA (MTA) and Magnotox-alphaB (MTB) with a commercially available toxin binder, Mycofix PlusMTV INSIDE (MF) in alleviating the pernicious effects of aflatoxin B1 (AFB1) in laying hens.

      • Natural toxins
      • Aflatoxins
      • Mycotoxins
  6. Compound mycotoxin detoxifier alleviating aflatoxin B1 toxic effects on broiler growth performance, organ damage and gut microbiota

    • Poultry Science
    • The aim of this study was to evaluate the effects of compound mycotoxin detoxifier (CMD) on alleviating the toxic effect of aflatoxin B1 (AFB1) for broiler growth performance. One-kilogram CMD consists of 667 g aflatoxin B1-degrading enzyme (ADE, 1,467 U/g), 200 g montmorillonite and 133 g compound probiotics (CP). The feeding experiment was divided into 2 stages (1–21 d and 22–42 d).

      • Natural toxins
      • Aflatoxins
      • Mycotoxins
  7. Research Note: Taraxasterol alleviates aflatoxin B1-induced oxidative stress in chicken primary hepatocytes

    • Poultry Science
    • Aflatoxin B1 (AFB1) is the most toxic subtype of aflatoxin in feed. Poultry is sensitive to AFB1, and the liver is the main target organ of AFB1. Our previous studies have shown that taraxasterol isolated from the traditional Chinese medicinal herb Taraxacum has protective effects against immune-mediated and alcoholic-induced liver injuries.

      • Natural toxins
      • Aflatoxins
      • Mycotoxins
  8. Mycotoxins binder supplementation alleviates aflatoxin B1 toxic effects on the immune response and intestinal barrier function in broilers

    • Poultry Science
    • This experiment was conducted to evaluate whether a commercial mycotoxins-binder, XL, could effectively attenuate the negative effects of Aflatoxin B1 (AFB1) on growth performance, immunological function, and intestinal health in birds.

      • Natural toxins
      • Aflatoxins
      • Mycotoxins
  9. The preventive effect and mechanisms of adsorbent supplementation in low concentration aflatoxin B1 contaminated diet on subclinical symptom and histological lesions of broilers

    • Poultry Science
    • This study aimed to investigate the subclinical symptom and histological lesions of 21-day-old and 42-day-old broilers exposure to low concentration aflatoxin B1 (AFB1), and the preventive effect with adsorbent (Toxo-MX) supplementation. A total of 576 one-day-old Arbor Acres broilers were randomly allotted into 6 treatments 8 replicates and 12 birds per cage, fed with 0 ppb, 60 ppb and 120 ppb AFB1 contamination diet with or without Toxo-MX supplementation.

      • Natural toxins
      • Aflatoxins
      • Mycotoxins
  10. Effects of Lactobacillus salivarius supplementation on the growth performance, liver function, meat quality, immune responses and Salmonella Pullorum infection resistance of broilers challenged with Aflatoxin B1

    • Poultry Science
    • Aflatoxin B1 (AFB1) is one of the most toxic mycotoxins. It has been reported that dietary exposure to AFB1 is related to the low growth performance, immunosuppression, and high susceptibility to infectious diseases of chickens. The aim of the present study was to evaluate the protective effects of Lactobacillus salivarius on broiler chickens challenged with AFB1.

      • Bacterial pathogens
      • Salmonella
      • Natural toxins
      • Aflatoxins
      • Mycotoxins
  11. Mycotoxins binder supplementation alleviates aflatoxin B1 toxic effects on the immune response and intestinal barrier function in broilers

    • Poultry Science
    • Author(s): Yujiao Lai, Meng Sun, Yang he, Jiaqi Lei, Yanming Han, Yuanyuan Wu, Bai Dongying, Yuming Guo, Bingkun Zhang

      • Aflatoxins
      • Natural toxins
  12. Effects of Lactobacillus salivarius supplementation on the growth performance, liver function, meat quality, immune responses and Salmonella Pullorum infection resistance of broilers challenged with Aflatoxin B1

    • Poultry Science
    • Author(s): Xueping Chen, Muhammad Ishfaq, Jian Wang Aflatoxin B1 (AFB1) is one of the most toxic mycotoxins. It has been reported that dietary exposure to AFB1 is related to the low growth performance, immunosuppression and high susceptibility to infectious diseases of chickens. The aim of the present study was to evaluate the protective effects of Lactobacillus salivarius on broiler chickens challenged with AFB1.

      • Bacterial pathogens
      • Salmonella
      • Natural toxins
      • Aflatoxins
  13. The Preventive Effect and Mechanisms of Adsorbent Supplementation in Low Concentration Aflatoxin B1 Contaminated Diet on Sub-clinical Symptom and Histological Lesions of Broilers

    • Poultry Science
    • Author(s): Kun Xie, Xi He, Guili Hu, Haihan Zhang, Yuguang Chen, De-Xing Hou, Zehe Song

      • Aflatoxins
      • Natural toxins
  14. Morin alleviates Aflatoxin B1-induced liver and kidney injury by inhibiting heterophil extracellular traps release, oxidative stress and inflammatory responses in chicks

    • Poultry Science
    • Author(s): Xinxin Gao, Jingnan Xu, Liqiang Jiang, Wei Liu, Hongrong Hong, Yuxiao Qian, Shurou Li, Wenlong Huang, Haiguang Zhao, Zhengtao Yang, Quan Liu, Zhengkai Wei

      • Aflatoxins
      • Natural toxins
  15. Protective effects of lycopene on mitochondrial oxidative injury and dysfunction in the liver of aflatoxin B1-exposed broilers

    • Poultry Science
    • Author(s): X.L. Wan, N. Li, Y.J. Chen, X.S. Chen, Z. Yang, L. Xu, H.M. Yang, Z.Y. Wang

      • Aflatoxins
      • Natural toxins
  16. Protective effect of glutathione S-transferase enzyme activity against aflatoxin B1 in poultry species: Relationship between glutathione S-transferase enzyme kinetic parameters, and resistance to aflatoxin B1

    • Poultry Science
    • Author(s): Hansen W. Murcia, Gonzalo J. Diaz

      • Natural toxins
      • Aflatoxins
  17. Methionine alleviates aflatoxinb1-induced broiler chicks embryotoxicity through inhibition of caspase-dependent apoptosis and enhancement of cellular antioxidant status

    • Poultry Science
    • Author(s): Hamada Elwan, Chao Xie, L.P. Miao, Xinyang Dong, Xiao‐ting Zou, Mohamed Mohany, Mohammed M Ahmed, Salim S Al-Rejaie, S.S. Elnesr

      • Aflatoxins
      • Natural toxins
  18. Marine algal polysaccharides alleviate aflatoxin B1-induced bursa of Fabricius injury by regulating redox and apoptotic signaling pathway in broilers

    • Poultry Science
    • Author(s): Yan Guo, Balamuralikrishnan Balasubramanian, Zhi-Hui Zhao, Wen-Chao Liu

      • Aflatoxins
      • Natural toxins
  19. Evaluation of berberine efficacy in reducing the effects of aflatoxin B1 and ochratoxin A added to male broiler rations

    • Poultry Science
    • Author(s): Pouyan Malekinezhad, Laura E. Ellestad, Nazar Afzali, Seyed Homayoun Farhangfar, Arash Omidi, Abbas Mohammadi

      • Aflatoxins
      • Mycotoxins
      • Natural toxins
  20. Effects of Licorice Extract, Probiotic, Toxin Binder and Poultry Litter Biochar on Performance, blood and Liver tissue indices of Broiler chickens Exposed to Aflatoxin-B1

    • Poultry Science
    • Author(s): Nasrin Rashidi, Ali Khatibjoo, Kamran Taherpour, Mohammad Akbari-Gharaei, Hassan Shirzadi

      • Natural toxins
      • Aflatoxins
  21. Transcriptomic alterations induced by aflatoxin B1 and ochratoxin A in LMH cell line

    • Poultry Science
    • Author(s): So-Young Choi, Tae Hyun Kim, Min-Wook Hong, Tae Sub Park, Hyojeong Lee, Sung-Jin Lee

      • Aflatoxins
      • Mycotoxins
      • Natural toxins
  22. Water-soluble substances of wheat: a potential preventer of aflatoxin B1-induced liver damage in broilers

    • Poultry Science
    • ABSTRACTAflatoxin B1 (AFB1) is very harmful for broiler production and public health. The water-soluble castoff in gluten production, i.e., the water-soluble substances of wheat (WSW) that contains 14% pentosan has positive effect on animal nutrient absorption, immunity, and antioxidation. Our study aims to investigate the preventive effects of WSW against AFB1-induced broiler liver injury.

      • Aflatoxins
      • Natural toxins
  23. A method to culture chicken enterocytes and their characterization

    • Poultry Science
    • ABSTRACTEnterocytes function as both absorptive and protective components of intestine that come in close contact with a variety of enteric factors, such as dietary, microbial, and parasites, that have potential to affect the organismal health. Understanding how enterocytes interact with this complex array of factors may help improve gut health particularly in the context of poultry production where it is also linked to food safety issues.

      • Aflatoxins
      • Natural toxins
  24. Effect of cysteamine hydrochloride supplementation on the growth performance, enterotoxic status, and glutathione turnover of broilers fed aflatoxin B1 contaminated diets

    • Poultry Science
    • ABSTRACTThis study aimed to investigate the effect of cysteamine hydrochloride (CSH) supplementation on the growth performance, opportunistic bacteria and enterotoxic markers, visceral lesions, glutathione turnover, and inflammatory factors of broilers fed diets contaminated with aflatoxin B1 (AFB1).

      • Aflatoxins
      • Bacterial pathogens
      • Natural toxins
  25. Effect of yeast cell wall on the growth performance and gut health of broilers challenged with aflatoxin B 1 and necrotic enteritis

    • Poultry Science
    • AbstractThis study aimed to investigate the effect of yeast cell walls (YCW) on the growth performance, visceral lesions, intestinal integrity, enterotoxicity, and bacteria of broilers challenged with aflatoxin B1 (AF) and necrotic enteritis (NE) from 1 to 21 d of age. A total of 576 one-day-old broilers were assigned to a 2 × 2 × 2 design for diets containing AFB1 (0 or 40 μg/kg), NE (challenged or unchallenged), or YCW (0 or 500 mg/kg).

      • Clostridium perfringens
      • Aflatoxins
      • Bacterial pathogens
      • Natural toxins