Research Publications (Food Safety)

by Mollie Virgo, Serge Mostowy, Brian T. Ho

by Jianbo Yuan, Yang Yu, Shihao Li, Xiaojun Zhang, Chuntao Zhang, Roujing Li, Jie Hu, Shuqing Si, Chengyi Zhang, Jianhai Xiang, Fuhua Li Vibriosis is one of the most serious diseases that commonly occurs in aquatic animals, thus, shaping a steady inherited resistance trait in organisms has received the highest priority in aquaculture. Whereas, the mechanisms underlying the development of such a resistance trait are mostly elusive.

by Nutthapon Sangklai, Premruethai Supungul, Pattana Jaroenlak, Anchalee Tassanakajon The microsporidian Enterocytozoon hepatopenaei (EHP) is a fungi-related, spore-forming parasite. EHP infection causes growth retardation and size variation in shrimp, resulting in severe economic losses. Studies on shrimp immune response have shown that several antimicrobial peptides (AMPs) were upregulated upon EHP infection.

by Dhira Saraswati Anggramukti, Eiji Ishii, Andre Pratama, Mohamad Al Kadi, Tetsuya Iida, Toshio Kodama, Shigeaki Matsuda Vibrio parahaemolyticus is the leading cause of seafood-borne gastroenteritis in humans worldwide. The major virulence factor responsible for the enteropathogenicity of this pathogen is type III secretion system 2 (T3SS2), which is encoded on the 80-kb V.

by Hao-Ching Wang, Shin-Jen Lin, Han-Ching Wang, Ramya Kumar, Phuoc Thien Le, Jiann-Horng Leu Photorhabdus insect-related toxins A and B (PirA and PirB) were first recognized as insecticidal toxins from Photorhabdus luminescens. However, subsequent studies showed that their homologs from Vibrio parahaemolyticus also play critical roles in the pathogenesis of acute hepatopancreatic necrosis disease (AHPND) in shrimps.

by Jiandong Chen, Hyuntae Byun, Qianxuan She, Zhi Liu, Karl-Gustav Ruggeberg, Qinqin Pu, I-Ji Jung, Dehao Zhu, Mary R. Brockett, Ansel Hsiao, Jun Zhu Vibrio cholerae is the etiologic agent of the severe human diarrheal disease cholera. To colonize mammalian hosts, this pathogen must defend against host-derived toxic compounds, such as nitric oxide (NO) and NO-derived reactive nitrogen species (RNS).

by Andrew J. Van Alst, Lucas M. Demey, Victor J. DiRita Vibrio cholerae respires both aerobically and anaerobically and, while oxygen may be available to it during infection, other terminal electron acceptors are proposed for population expansion during infection. Unlike gastrointestinal pathogens that stimulate significant inflammation leading to elevated levels of oxygen or alternative terminal electron acceptors, V.

by Bao-Rui Zhao, Xin-Xin Wang, Xian-Wei Wang Flagellin is a key bacterial virulence factor that can stimulate molecular immune signaling in both animals and plants. The detailed mechanisms of recognizing flagellin and mounting an efficient immune response have been uncovered in vertebrates; however, whether invertebrates can discriminate flagellin remains largely unknown.

by Xiaoye Liang, Tong-Tong Pei, Hao Li, Hao-Yu Zheng, Han Luo, Yang Cui, Ming-Xuan Tang, Ya-Jie Zhao, Ping Xu, Tao Dong The type VI secretion system (T6SS) is a spear-like nanomachine found in gram-negative pathogens for delivery of toxic effectors to neighboring bacterial and host cells. Its assembly requires a tip spike complex consisting of a VgrG-trimer, a PAAR protein, and the interacting effectors. However, how the spike controls T6SS assembly remains elusive.

by Yi Gong, Xiaoyuan Wei, Wanwei Sun, Xin Ren, Jiao Chen, Jude Juventus Aweya, Hongyu Ma, Kok-Gan Chan, Yueling Zhang, Shengkang Li

by Yao Ma, Xiaoman Yang, Hongou Wang, Zixin Qin, Chunrong Yi, Changping Shi, Mei Luo, Guozhong Chen, Jin Yan, Xiaoyun Liu, Zhi Liu

by Waruntorn Luangtrakul, Pakpoom Boonchuen, Phattarunda Jaree, Ramya Kumar, Han-Ching Wang, Kunlaya Somboonwiwat

by Aftab Nadeem, Athar Alam, Eric Toh, Si Lhyam Myint, Zia ur Rehman, Tao Liu, Marta Bally, Anna Arnqvist, Hui Wang, Jun Zhu, Karina Persson, Bernt Eric Uhlin, Sun Nyunt Wai

by Carmen Schwechheimer, Kassidy Hebert, Sarvind Tripathi, Praveen K. Singh, Kyle A. Floyd, Elise R. Brown, Monique E. Porcella, Jacqueline Osorio, Joseph T. M. Kiblen, Fernando A. Pagliai, Knut Drescher, Seth M. Rubin, Fitnat H. Yildiz

by Samit Watve, Kelsey Barrasso, Sarah A. Jung, Kristen J. Davis, Lisa A. Hawver, Atul Khataokar, Ryan G. Palaganas, Matthew B. Neiditch, Lark J. Perez, Wai-Leung Ng

Tra-My Duong-Nu, Kwangjoon Jeong, Seol Hee Hong, Sao Puth, Soo Young Kim, Wenzhi Tan, Kwang Ho Lee, Shee Eun Lee, Joon Haeng Rhee

Sivan Laviad-Shitrit, Ido Izhaki, Malka Halpern

Alyson R. Warr, Troy P. Hubbard, Diana Munera, Carlos J. Blondel, Pia Abel zur Wiesch, Sören Abel, Xiaoxue Wang, Brigid M. Davis, Matthew K. Waldor

S. Peter Howard, Leandro F. Estrozi, Quentin Bertrand, Carlos Contreras-Martel, Timothy Strozen, Viviana Job, Alexandre Martins, Daphna Fenel, Guy Schoehn, Andréa Dessen

Hui Wang, Xiaolin Xing, Jipeng Wang, Bo Pang, Ming Liu, Jessie Larios-Valencia, Tao Liu, Ge Liu, Saijun Xie, Guijuan Hao, Zhi Liu, Biao Kan, Jun Zhu

Shilpa Gadwal, Tanya L. Johnson, Henriette Remmer, Maria Sandkvist

Frederico Alisson-Silva, Janet Z. Liu, Sandra L. Diaz, Lingquan Deng, Mélanie G. Gareau, Ronald Marchelletta, Xi Chen, Victor Nizet, Nissi Varki, Kim E. Barrett, Ajit Varki

Araceli E. Santiago, Michael B. Yan, Tracy H. Hazen, Brooke Sauder, Mario Meza-Segura, David A. Rasko, Melissa M. Kendall, Fernando Ruiz-Perez, James P. Nataro

Marcela de Souza Santos, Dor Salomon, Kim Orth

Audrey S. Vanhove, Saiyu Hang, Vidhya Vijayakumar, Adam CN Wong, John Asara, Paula I. Watnick