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Food Safety Publications

The Food Safety Publications tracks research that is published across national and international peer-reviewed journals. Recent articles are available ahead of print and searchable by Journal, Article Title, and Category. The research publications are tracked across six categories: Bacterial Pathogens, Chemical Contaminants, Natural Toxins, Parasites, Produce Safety, and Viruses. Articles produced by USDA Grant Funding Agencies and FDA Grant Funding Agencies are also tracked.

Displaying 1 - 25 of 357

  1. Inhibition of Virulence Gene Expression in Salmonella Dublin, Escherichia coli F5 and Clostridium perfringens Associated With Neonatal Calf Diarrhea by Factors Produced by Lactic Acid Bacteria During Fermentation of Cow Milk

    • Thu, 05/12/2022 - 04:00
    • Frontiers in Microbiology
    • Diarrhea is a major health problem in neonatal and young calves worldwide. It can be caused by a variety of infectious agents, including the bacteria Salmonella enterica serovar Dublin (S. Dublin), enterotoxigenic Escherichia coli (ETEC), and Clostridium perfringens. Preventive alternatives to antibiotic treatment should be identified.

      • Bacterial pathogens
      • Clostridium perfringens
      • Salmonella
  2. Survival of Clostridium perfringens, Staphylococcus aureus, Listeria monocytogenes and Salmonella enterica in alternatively cured ham during cooking and process deviations

    • Fri, 05/06/2022 - 04:00
    • LWT
    • Boneless hams were prepared with four different brines and inoculated on the surface and at a depth of 1 cm with multiple strains of Clostridium perfringens, Staphylococcus aureus, Listeria monocytogenes and Salmonella enterica. Hams were processed with a standard, low relative humidity or interrupted process cycle to an end point temperature of 70 °C. Microbiological populations were determined at the beginning, mid-point and end of the cycles.

      • Bacterial pathogens
      • Clostridium perfringens
      • Listeria monocytogenes
      • Salmonella
      • Staphylococcus aureus
  3. Outbreaks of Acute Necrotic Enteritis and Haemolytic Crisis and Renal Disease Associated with Clostridium perfringens in Captive Toucans (Ramphastos spp)

    • Thu, 04/28/2022 - 04:00
    • Journal of Comparative Pathology
    • Four toco toucans (Ramphastos toco), one channel-billed toucan (Ramphastos vitellinus) and one white-throated toucan (Ramphastos tucanus) died in two disease outbreaks in the same aviary in 2011 and 2016.

      • Bacterial pathogens
      • Clostridium perfringens
  4. Inhibitory effects of reuterin on biofilm formation, quorum sensing and virulence genes of Clostridium perfringens

    • Thu, 04/21/2022 - 04:00
    • LWT
    • Clostridium perfringens (C. perfringens) have been considered as one of the most common causes of human and veterinary gastrointestinal diseases. Reuterin is a broad-spectrum antimicrobial agent produced by certain Lactobacillus reuteri (L. reuteri) strains.

      • Bacterial pathogens
      • Clostridium perfringens
  5. Dietary ellagic acid ameliorated Clostridium perfringens-induced subclinical necrotic enteritis in broilers via regulating inflammation and cecal microbiota

    • Thu, 04/21/2022 - 04:00
    • Journal of Animal Science and Biotechnology
    • Background Subclinical necrotic enteritis (SNE), a common intestinal disease of broiler caused by Clostridium perfringens, could reduce production performance of broilers by chronic intestinal damage and poor absorption of nutrients. Ellagic acid (EA) has been reported to present antioxidant and anti-inflammatory properties on human and animals in many aspects. This study was conducted to evaluate the effect and mechanism of EA in relieving SNE in broilers induced by C.

      • Bacterial pathogens
      • Clostridium perfringens
  6. New Mutants of Epsilon Toxin from Clostridium perfringens with an Altered Receptor-Binding Site and Cell-Type Specificity

    • Sun, 04/17/2022 - 04:00
    • Toxins
    • Epsilon toxin (Etx) from Clostridium perfringens is the third most potent toxin after the botulinum and tetanus toxins. Etx is the main agent of enterotoxemia in ruminants and is produced by Clostridium perfringens toxinotypes B and D, causing great economic losses. Etx selectively binds to target cells, oligomerizes and inserts into the plasma membrane, and forms pores.

      • Bacterial pathogens
      • Clostridium botulinum
      • Clostridium perfringens
  7. Polyphenolic phytochemicals as natural feed additives to control bacterial pathogens in the chicken gut

    • Tue, 04/12/2022 - 04:00
    • Archives of Microbiology
    • Poultry provides an important protein source consumed globally by human population, and simultaneously, acts as a substantial reservoir of antibiotic resistant bacterial species such as Escherichia coli, Salmonella, Campylobacter, Clostridium perfringens. These bacterial species can include commensal strains with beneficial roles on poultry health and productivity, and pathogenic strains not only to poultry but zoonotically to man.

      • Bacterial pathogens
      • Campylobacter
      • Clostridium perfringens
      • Salmonella
  8. Prevalence, Antibiotic Resistance, Toxin-Typing and Genotyping of Clostridium perfringens in Raw Beef Meats Obtained from Qazvin City, Iran

    • Sat, 03/05/2022 - 12:00
    • Antibiotics
    • Clostridium perfringens is one of the highest prevailing spore-forming foodborne pathogens, which is widely distributed and causes severe disease and outbreaks in humans and animals. Raw meat and poultry are the main vehicles of this pathogen. In this study, we investigated the prevalence, antibiotic resistance pattern, toxin-encoding genes and genetic diversity of C.

      • Bacterial pathogens
      • Clostridium perfringens
  9. Eurotium cristatum, a Probiotic Fungus from Fuzhuan Brick Tea, and Its Polysaccharides Ameliorated DSS-Induced Ulcerative Colitis in Mice by Modulating the Gut Microbiota

    • Thu, 03/03/2022 - 12:00
    • Journal of Agricultural and Food Chemistry
    • Eurotium cristatum is a potential probiotic fungus that is used to enhance Fuzhuan tea quality through fermentation and could reduce obesity by modulating gut dysbiosis. This study aimed to investigate the effects and possible mechanisms of killed E. cristatum (KEC) and its polysaccharides (ECP) in ulcerative colitis (UC) relief. KEC and ECP were administered to mice with dextran sulfate sodium-induced UC.

      • Bacterial pathogens
      • Clostridium perfringens
  10. A Highly Specific Holin-Mediated Mechanism Facilitates the Secretion of Lethal Toxin TcsL in Paeniclostridium sordellii

    • Wed, 02/09/2022 - 06:00
    • Toxins
    • Protein secretion is generally mediated by a series of distinct pathways in bacteria. Recently, evidence of a novel bacterial secretion pathway involving a bacteriophage-related protein has emerged. TcdE, a holin-like protein encoded by toxigenic isolates of Clostridioides difficile, mediates the release of the large clostridial glucosylating toxins (LCGTs), TcdA and TcdB, and TpeL from C.

      • Bacterial pathogens
      • Clostridium perfringens
  11. Effects of postweaning supplementation of immunomodulatory feed ingredient on circulating cytokines and microbial populations in programmed fed beef heifers

    • Mon, 01/31/2022 - 06:00
    • Journal of Animal Science
    • The objective was to determine the effects of an immunomodulatory feed ingredient following weaning on cytokine expression and fecal microbial populations of heifers. Commercial Angus heifers (n = 72) were weaned (227 ± 7 d of age), blocked by BW (n = 9 blocks), and randomly assigned to one of two pens per block. Pens within weight block (four heifers per pen) were then randomly assigned to treatments.

      • Bacterial pathogens
      • Clostridium perfringens
      • Salmonella
  12. Tracking Clostridium perfringens strains from breeding duck farm to commercial meat duck farm by multilocus sequence typing

    • Thu, 01/27/2022 - 12:00
    • Veterinary Microbiology
    • Clostridium perfringens (C. perfringens) is an important zoonotic food-borne pathogenic microorganism. Currently, there are many reports on the prevalence of C. perfringens in poultry farms, while few studies on the prevalence and infection source of C. perfringens in egg hatcheries. The present study was undertaken to investigate and track C.

      • Bacterial pathogens
      • Clostridium perfringens
  13. Platelet Endothelial Cell Adhesion Molecule 1 (CD31) Is Essential for Clostridium perfringens Beta-Toxin Mediated Cytotoxicity in Human Endothelial and Monocytic Cells

    • Fri, 01/21/2022 - 12:00
    • Toxins
    • Beta toxin (CPB) is a small hemolysin beta pore-forming toxin (β-PFT) produced by Clostridium perfringens type C. It plays a central role in the pathogenesis of necro-hemorrhagic enteritis in young animals and humans via targeting intestinal endothelial cells. We recently identified the membrane protein CD31 (PECAM-1) as the receptor for CPB on mouse endothelial cells.

      • Bacterial pathogens
      • Clostridium perfringens
  14. Antimicrobial activity of sophorolipids against Eimeria maxima and Clostridium perfringens, and their effect on growth performance and gut health in necrotic enteritis

    • Sun, 01/16/2022 - 06:00
    • Poultry Science
    • The in vitro antimicrobial activity of sophorolipids (SLs) against Eimeria maxima and Clostridium perfringens, and the in vivo effects of SLs on growth performance and gut health in necrotic enteritis (NE)-afflicted broiler chickens were studied. To test the direct killing effects of SLs on enteric pathogens, 2.5 × 105 freshly prepared sporozoites of each Eimeria acervulina, E. maxima, and E.

      • Bacterial pathogens
      • Clostridium perfringens
  15. Intestinal changes and immune responses during Clostridium perfringens-induced necrotic enteritis in broiler chickens

    • Sun, 01/16/2022 - 06:00
    • Poultry Science
    • Clostridium perfringens-induced necrotic enteritis (NE) is an economically important disease of broiler chickens. The present study evaluated the effect of C. perfringens on the intestinal histomorphometry, enteric microbial colonization, and host immune responses using 3 experimental NE reproduction methods.

      • Bacterial pathogens
      • Clostridium perfringens
  16. Alleviating effect of dietary supplementation of benzoic acid, Enterococcus faecium and essential oil complex on coccidia and Clostridium perfringens challenge in laying hens

    • Fri, 01/14/2022 - 06:00
    • Poultry Science
    • The purpose of this experiment is to explore the effects of dietary supplementation of benzoic acid, Enterococcus faecium, and essential oil complex (BEC) on coccidia and Clostridium perfringens challenge in laying hens.

      • Bacterial pathogens
      • Clostridium perfringens
  17. Occurrence of Clostridium spp. in ewe’s milk: enumeration and identification of isolates

    • Fri, 01/14/2022 - 06:00
    • Dairy Science
    • The presence of gas-producing clostridia in ewe’s milk can lead to the occurrence of late-blowing defects in cheeses. However, data on this aspect are limited. In the present study, using the most probable number (MPN) method, clostridial spores were enumerated in 527 ewe’s milk samples collected in the Grosseto Province (Tuscany, Italy) from autumn 2014 to summer 2015.

      • Bacterial pathogens
      • Clostridium perfringens
  18. Predictive modeling and probabilistic risk assessment of Clostridium perfringens in hamburgers and sandwiches

    • Fri, 01/14/2022 - 06:00
    • Food Science and Biotechnology
    • This study aimed to develop a mathematical model for the survival of Clostridium perfringens in hamburgers and sandwiches and to evaluate their microbial risk. The primary model was developed in hamburgers using 4 strains of C. perfringens at 5, 10, 15, 25 and 37 °C, and the kinetic parameters of the primary model were fitted well with the Weibull model (R2 ≥ 0.95).

      • Bacterial pathogens
      • Clostridium perfringens
  19. Severe gastroenteropathy associated with Clostridium perfringens isolation in starving juvenile sturgeons

    • Wed, 01/12/2022 - 22:17
    • Journal of Fish Diseases
    • Journal of Fish Diseases, EarlyView.

      • Bacterial pathogens
      • Clostridium perfringens
  20. Organic Acids and Nature Identical Compounds Can Increase the Activity of Conventional Antibiotics Against Clostridium Perfringens and Enterococcus Cecorum In Vitro

    • Wed, 01/12/2022 - 22:17
    • The Journal of Applied Poultry Research
    • SUMMARY In a global context of increased antibiotic resistance, feed additives with enhanced antimicrobial properties are a useful and increasingly needed strategy. Organic acids (OA) and botanical molecules such as nature identical compounds (NIC) have been shown to be effective against bacterial infections based on their antimicrobial activity.

      • Bacterial pathogens
      • Clostridium perfringens
  21. Operational Antecedents Associated with Clostridium perfringens Outbreaks in Retail Food Establishments, United States, 2015–2018

    • Wed, 01/12/2022 - 22:17
    • Foodborne Pathogens and Disease
    • Clostridium perfringens is a common foodborne pathogen, frequently associated with improper cooking, and cooling or reheating of animal products. The U.S. Food and Drug Administration Food Code outlines proper food preparation practices to prevent foodborne outbreaks; however, retail food establishments continue to have C. perfringens outbreaks.

      • Bacterial pathogens
      • Clostridium perfringens
  22. The Effects of Garlic and Red Chilli Pepper Powder on Physicochemical, Microbiological, and Sensory Properties of Cincalok

    • Wed, 01/12/2022 - 22:17
    • International Journal of Food Science
    • Cincalok, a traditional fermented shrimp, is prepared by mixing rebon shrimps (Acetes sp) with coarse salt and granulated sugar in a certain ratio. This research was aimed at studying the effect of adding garlic and red chilli pepper powder on the physicochemical, microbiological, and sensory properties of cincalok.

      • Bacterial pathogens
      • Bacillus cereus
      • Clostridium perfringens
      • Staphylococcus aureus
  23. Virulent phage vB_CpeP_HN02 inhibits Clostridium perfringens on the surface of the chicken meat

    • Wed, 01/12/2022 - 22:17
    • International Journal of Food Microbiology
      • Bacterial pathogens
      • Clostridium perfringens
  24. A simple method for purification of epsilon toxin of Clostridium perfringens type D for serum neutralization assay

    • Wed, 01/12/2022 - 22:17
    • Journal of Microbiological Methods
      • Bacterial pathogens
      • Clostridium perfringens
  25. A triple-sugar regulated Salmonella vaccine protects against Clostridium perfringens-induced necrotic enteritis in broiler chickens

    • Wed, 01/12/2022 - 22:17
    • Poultry Science
    • Gram-positive Clostridium perfringens type G, the causative agent of necrotic enteritis (NE), has gained more attention in the poultry industry due to governmental restrictions on the use of growth-promoting antibiotics in poultry feed.

      • Bacterial pathogens
      • Clostridium perfringens
      • Salmonella