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Research Publications (Food Safety)

The Food Safety Publications tracks research that is published across national and international peer-reviewed journals. Recent articles are available ahead of print and searchable by Journal, Article Title, and Category. The research publications are tracked across six categories: Bacterial Pathogens, Chemical Contaminants, Natural Toxins, Parasites, Produce Safety, and Viruses. Articles produced by USDA Grant Funding Agencies and FDA Grant Funding Agencies are also tracked.

Displaying 1 - 25 of 2542

  1. Mitigating the toxicity of palmitoylated analogue of α-melanocyte stimulating hormone(11–13) by conjugation with gold nanoparticle: characterisation and antibacterial efficacy against methicillin sensitive and resistant Staphylococccus aureus

    • Thu, 08/18/2022 - 04:00
    • World Journal of Microbiology and Biotechnology
    • In an attempt to develop potent and non-toxic antimicrobial agent, the palmitoylated analogue of α-melanocyte stimulating hormone(11–13), Pal-α-MSH(11–13) was conjugated with gold nanoparticles (GNPs) for the first time and the efficacy of derived complex was investigated against two strains of Staphylococccus aureus. The GNPs were synthesized using tri-sodium citrate as reductant and Pal-α-MSH(11–13) was conjugated thereafter.

      • Bacterial pathogens
      • Staphylococcus aureus
  2. Phage-Related Ribosomal Proteases (Prps): Discovery, Bioinformatics, and Structural Analysis

    • Wed, 08/17/2022 - 04:00
    • Antibiotics
    • Many new antimicrobials are analogs of existing drugs, sharing the same targets and mechanisms of action. New antibiotic targets are critically needed to combat the growing threat of antimicrobial-resistant bacteria. Phage-related ribosomal proteases (Prps) are a recently structurally characterized antibiotic target found in pathogens such as Staphylococcus aureus, Clostridioides difficile, and Streptococcus pneumoniae.

      • Bacterial pathogens
      • Staphylococcus aureus
  3. Different European Perspectives on the Treatment of Clinical Mastitis in Lactation

    • Wed, 08/17/2022 - 04:00
    • Antibiotics
    • As part of the European Network for Optimization of Veterinary Antimicrobial Treatment (ENOVAT), a webinar on the topic “Mastitis Treatment in Lactation” was held, in which eight mastitis experts from different European countries (Spain, The Netherlands, Estonia, Ireland, Poland, Finland, Germany, and Italy) presented their treatment approaches for clinical mastitis in lactation.

      • Bacterial pathogens
      • Staphylococcus aureus
  4. Microcalorimetric Investigations of Reversible Staphylococcal Enterotoxin Unfolding

    • Tue, 08/16/2022 - 04:00
    • Toxins
    • Staphylococcal food poisoning (SFP) is a common food-borne illness often associated with contamination during food handling. The genes for Staphylococcal enterotoxin (SE) isoforms SEA and SEB are frequently detected in human nasal Staphylococcus aureus isolates and these toxins are commonly associated with SFP. Past studies described the resistance of preformed SE proteins to heat inactivation and their reactivation upon cooling in foods.

      • Bacterial pathogens
      • Staphylococcus aureus
  5. Genotypes of Staphylococcus aureus Clinical Isolates Are Associated with Phenol-Soluble Modulin (PSM) Production

    • Tue, 08/16/2022 - 04:00
    • Toxins
    • Phenol-soluble modulins (PSMs) are important S. aureus virulence factors that cause cytolysis, mast cell degranulation, and stimulate inflammatory responses. In this study, PSM production by S. aureus clinical isolates was measured by liquid chromatography/mass spectrometry (LC-MS) and correlated with staphylococcal protein A (spa) type and staphylococcal cassette chromosome mec (SCCmec) type. Of 106 S. aureus clinical isolates, 50 (47.2%) corresponded to methicillin-susceptible S.

      • Bacterial pathogens
      • Staphylococcus aureus
  6. Comparative genomics of dairy-associated Staphylococcus aureus from selected sub-Saharan African regions reveals milk as reservoir for human-and animal-derived strains and identifies a putative animal-related clade with presumptive novel siderophore

    • Mon, 08/15/2022 - 04:00
    • Frontiers in Microbiology
    • Staphylococcus aureus infection is considered to be a neglected tropical disease with huge impact on human and animal health alike. Dairy production in sub-Saharan Africa (SSA) relies heavily on various animals such as cows, goats, and camels, depending on the region. S. aureus causes mastitis and exhibits high prevalence in raw milk. The population structure including genotypic and phenotypic traits of dairy S. aureus in relation to animal and human isolates is, however, unknown for SSA.

      • Bacterial pathogens
      • Staphylococcus aureus
  7. Identification of small molecules targeting homoserine acetyl transferase from Mycobacterium tuberculosis and Staphylococcus aureus

    • Sun, 08/14/2022 - 04:00
    • Scientific Reports
    • There is an urgent need to validate new drug targets and identify small molecules that possess activity against both drug-resistant and drug-sensitive bacteria. The enzymes belonging to amino acid biosynthesis have been shown to be essential for growth in vitro, in vivo and have not been exploited much for the development of anti-tubercular agents. Here, we have identified small molecule inhibitors targeting homoserine acetyl transferase (HSAT, MetX, Rv3341) from M. tuberculosis.

      • Bacterial pathogens
      • Staphylococcus aureus
  8. Lactic acid bacteria and Staphylococcus carnosus fermentation as a means for eliminating 4‐alkyl branched odor fatty acids of mutton jerky and its effect on other quality characteristics

    • Sun, 08/14/2022 - 04:00
    • International Journal of Food Science & Technology
    • International Journal of Food Science &Technology, Accepted Article. Lactiplantibacilllus plantarum (Lp), Pediococcus pentosaceus (Pp) and Staphylococcus carnosus (Sc) were applied to remove the odor fatty acid and the effect on quality characteristics of mutton jerky were investigated. The results showed that the mixed strains, especially the Lp+Pp+Sc treatment, had a strong ability to remove odor.

      • Bacterial pathogens
      • Staphylococcus aureus
  9. Probe-based Loop-Mediated Isothermal Amplification Assay for Multi-target Quantitative Detection of Three Foodborne Pathogens in Seafood

    • Sat, 08/13/2022 - 04:00
    • Food Analytical Methods
    • Foodborne pathogens pose serious risks to human health and food safety. More than one pathogen exists in seafood. It is difficult for conventional culture methods to detect some foodborne pathogens simultaneously. Probe-based loop-mediated isothermal amplification is a feasible tool for achieving multi-objective detection of bacterial pathogens in a short time.

      • Bacterial pathogens
      • Salmonella
      • Staphylococcus aureus
      • Vibrio
  10. Antibacterial activity of Bacillus licheniformis B6 against viability and biofilm formation of foodborne pathogens of health importance

    • Sat, 08/13/2022 - 04:00
    • World Journal of Microbiology and Biotechnology
    • We studied a strain of Bacillus isolated from an artisanal tannery in Salta, Argentina. It was identified as Bacillus licheniformis B6 by 16 S phylogenetic analysis and MALDI TOF (GenBank accession code No. KP776730). The synthesis of lipopeptides by B6 and their antibacterial activity against clinical pathogenic strains was analyzed both in the cell-free supernatant (CFS) and in the crude fraction of lipopeptides (LF).

      • Bacterial pathogens
      • Staphylococcus aureus
  11. Plantaricin A reverses resistance to ciprofloxacin of multidrug‐resistant Staphylococcus aureus by inhibiting efflux pumps

    • Sat, 08/13/2022 - 04:00
    • Environmental Microbiology
    • Environmental Microbiology, EarlyView. Overexpression of Staphylococcus aureus efflux pumps is commonly associated with antibiotic resistance, causing conventional antibiotics to be unsuccessful in combating multidrug-resistant bacterial infections. Reducing the activity of the efflux pump is an urgently required to tackle this problem.

      • Bacterial pathogens
      • Staphylococcus aureus
  12. New Pyrazolo-Benzimidazole Mannich Bases with Antimicrobial and Antibiofilm Activities

    • Sat, 08/13/2022 - 04:00
    • Antibiotics
    • A new series of pyrazolo-benzimidazole hybrid Mannich bases were synthesized, characterized by 1H-NMR, 13C-NMR, IR, UV-Vis, MS, and elemental analysis. In vitro cytotoxicity of the new compounds studied on fibroblast cells showed that the newly synthesized pyrazolo-benzimidazole hybrid derivatives were noncytotoxic until the concentration of 1 μM and two compounds presented a high degree of biocompatibility.

      • Bacterial pathogens
      • Staphylococcus aureus
  13. Optimal dose of lactoferrin reduces the resilience of in vitro Staphylococcus aureus colonies

    • Sat, 08/13/2022 - 04:00
    • PLOS ONE
    • by Jagir R. Hussan, Stuart G. Irwin, Brya Mathews, Simon Swift, Dustin L. Williams, Jillian Cornish The rise in antibiotic resistance has stimulated research into adjuvants that can improve the efficacy of broad-spectrum antibiotics. Lactoferrin is a candidate adjuvant; it is a multifunctional iron-binding protein with antimicrobial properties.

      • Bacterial pathogens
      • Staphylococcus aureus
  14. Effects of Salt Stress on the Structure and Function of Oil-Contaminated Soil Bacteria

    • Fri, 08/12/2022 - 04:00
    • Water, Air, & Soil Pollution
    • Saline-alkali is one of the important environmental factors affecting oil-contaminated soil.

      • Bacterial pathogens
      • Staphylococcus aureus
  15. Phytochemical screening and antibacterial activity of Skimmia anquetilia N.P. Taylor and Airy Shaw: A first study from Kashmir Himalaya

    • Fri, 08/12/2022 - 04:00
    • Frontiers in Plant Science
    • The present study aimed to explore the antibacterial activity of various organic root extracts of Skimmia anquetilia N.P. Taylor and Airy Shaw and the identification of major functional groups and phytoconstituents through fourier transform infrared spectrometer (FTIR) and gas chromatography-mass spectrometer (GC-MS).

      • Bacterial pathogens
      • Salmonella
      • Staphylococcus aureus
  16. Glucose oxidase as an important yet overlooked factor determining the antibacterial activity of bee pollen and bee bread

    • Thu, 08/11/2022 - 04:00
    • European Food Research and Technology
    • Bee pollen (BP) and bee bread (BB) have attracted great attention due to their biological activities including antibacterial activity. However, the mechanism of antibacterial activity is largely unknown.

      • Bacterial pathogens
      • Staphylococcus aureus
  17. Comparative Study of the Physicochemical and Microbiological Quality of Liquid, Freeze-Dried, Hot Air-Dried, and Pasteurized Quail Eggs Produced in Benin

    • Thu, 08/11/2022 - 04:00
    • International Journal of Food Science
    • Nutrients in quail eggs can be affected by egg product processing technologies. However, freeze-drying would be the most suitable, but it is very costly and difficult to transfer to the quail egg production actors. This study is aimed at comparing the physicochemical and microbiological qualities of liquid, pasteurized, hot air-dried, and freeze-dried quail eggs. Liquid quail eggs were used as controls. The physicochemical and microbiological qualities were evaluated by conventional methods.

      • Bacterial pathogens
      • Salmonella
      • Staphylococcus aureus
  18. Complete Genome Sequence of Staphylococcus edaphicus Strain CCM 8731

    • Thu, 08/11/2022 - 04:00
    • Microbiology Resource Announcements
    • Microbiology Resource Announcements, Ahead of Print. Here, we present the complete genome sequence of Staphylococcus edaphicus strain CCM 8731, which was originally isolated from Ross Island, Antarctica. The 2,749,487-bp sequence contains 2,709 predicted genes, with a G+C content of 33.4%. The complete genome was assembled using a hybrid approach with Oxford Nanopore Technologies long-read sequencing and Illumina short-read sequencing.

      • Bacterial pathogens
      • Staphylococcus aureus
  19. Assessment of the antioxidant, antimicrobial and antibiofilm activities of essential oils for potential application of active chitosan films in food preservation

    • Wed, 08/10/2022 - 04:00
    • World Journal of Microbiology and Biotechnology
    • In the food industry, the development of microbial biofilms is a serious problem that leads to the contamination and deterioration of food products. To overcome that, our aim consists of searching for natural antimicrobial and non-toxic compounds (essential oils EOs), which might be used alone or adsorbed on natural biopolymer films (chitosan).

      • Bacterial pathogens
      • Staphylococcus aureus
  20. C-Locked Analogs of the Antimicrobial Peptide BP214

    • Wed, 08/10/2022 - 04:00
    • Antibiotics
    • BP214 is an all-D antimicrobial peptide amide, kklfkkilryl, which shows an excellent activity against colistin-resistant Acinetobacter baumannii and a low hemolytic activity. The aim of the present work was to investigate how C-terminus-to-side chain macrocyclization and fatty acid modification affect the antimicrobial and hemolytic activity of this peptide.

      • Bacterial pathogens
      • Staphylococcus aureus
  21. Antibiotic Resistance in Bacteria—A Review

    • Wed, 08/10/2022 - 04:00
    • Antibiotics
    • A global problem of multi-drug resistance (MDR) among bacteria is the cause of hundreds of thousands of deaths every year. In response to the significant increase of MDR bacteria, legislative measures have widely been taken to limit or eliminate the use of antibiotics, including in the form of feed additives for livestock, but also in metaphylaxis and its treatment, which was the subject of EU Regulation in 2019/6.

      • Bacterial pathogens
      • Campylobacter
      • Salmonella
      • Staphylococcus aureus
  22. Biosynthesis and biophysical elucidation of CuO nanoparticle from Nyctanthes arbor-tristis Linn Leaf

    • Wed, 08/10/2022 - 04:00
    • Applied Microbiology and Biotechnology
    • Copper oxide nanoparticles (CuO NPs) synthesis using an environmentally benign approach, as well as their antibacterial properties. Copper sulphate pentahydrate (CuSO4.5H2O) of different concentrations (2 mM, 5 mM and 10 mM) and aqueous Nyctanthes arbor-tristis leaf extract were used to make the CuO NPs.

      • Bacterial pathogens
      • Staphylococcus aureus
  23. Effect of inoculating mixed starter cultures of Lactobacillus and Staphylococcus on bacterial communities and volatile flavor in fermented sausages

  24. Short Tryptamine-Based Peptoids as Potential Therapeutics for Microbial Keratitis: Structure-Function Correlation Studies

    • Tue, 08/09/2022 - 04:00
    • Antibiotics
    • Peptoids are peptidomimetics that have attracted considerable interest as a promising class of antimicrobials against multi-drug-resistant bacteria due to their resistance to proteolysis, bioavailability, and thermal stability compared to their corresponding peptides. Staphylococcus aureus is a significant contributor to infections worldwide and is a major pathogen in ocular infections (keratitis). S.

      • Bacterial pathogens
      • Staphylococcus aureus
  25. Mode of action of elasnin as biofilm formation eradicator of methicillin-resistant Staphylococcus aureus

    • Mon, 08/08/2022 - 04:00
    • Frontiers in Microbiology
    • Biofilm is made up of microbes and their extracellular matrix, making microorganisms highly tolerant, resistant, and resilient to a wide range of antimicrobials. Biofilm treatment with conventional antimicrobial agents can accelerate the evolution and spread of resistance due to the reduced efficacy and increased gene transfer and differentiation within biofilms. Therefore, effective biofilm-targeting compounds are currently highly sought after.

      • Bacterial pathogens
      • Staphylococcus aureus