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3Rs Alternatives: Technologies, and Approaches

3Rs alternatives refer to the reduction, refinement, and replacement of animal use in research, testing, and teaching. The concept was developed by Russell and Burch in a 1959 book entitled Principles of Humane Experimental Technique. A fundamental goal of the Animal Welfare Act and the accompanying regulations is the minimization of animal pain and distress via the consideration of alternatives and alternative methods.

Humane Society of the United States and Proctor & Gamble.

The goal of this web site is to advance non-animal methods of toxicity testing through online discussion and information exchange.