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Allergen Specific Antibody Binding Characteristics and Longitudinal Serological Changes to Purified Allergens


This project aims to examine the role that affinity/avidity (strength/quality) of antibody binding to major peanut allergens has in the persistence of peanut allergy.

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Unlike many food allergies, which are common in infancy, peanut allergy persists into adulthood, and multiple factors may be responsible for this, such as the strength or quality of antibody binding to peanut allergen(s).

<p>A group of 70 peanut allergic individuals will be followed for a period of two to five years. Levels and the affinities of total and peanut-specific antibodies in blood will be examined over this period.

<p>Find more about this project and other FSA food safety-related projects at the <a href="; target="_blank">Food Standards Agency Research webpage</a>.

St. Mary's Hospital, Manchester
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