Research Publications from Peer-Reviewed Journals

The Research Publications track research that is published across national and international peer-reviewed journals. The most recent articles are available ahead of print and searchable by Journal Title, Subject, USDA Grant Funding Agencies or FDA Grant Funding Agencies. The research publications are tracked across five subject areas: Bacterial Pathogens, Chemical Contaminants, Natural Toxins, Parasites, and Viruses.

Sat, 07/11/2020 - 06:08
Author(s): Danlei Liu, Zilei Zhang, Shenwei Li, Qingping Wu, Peng Tian, Zilong Zhang, Dapeng Wang Human noroviruses (HuNoVs) are the primary non-bacterial pathogens causing acute gastroenteritis worldwide. Here we reported a co-infection of HuNoVs with different genotypes during an outbreak of gastroenteritis in travelers. The aim was to trace the source and transmission patterns of the...
Sat, 07/11/2020 - 06:08
Author(s): Ashrafur Rahman, Ali Asgary, Daniel Munther, Aamir Fazil, Ben A. Smith, Jianhong Wu We developed an agent-based gastric simulator for a human host to illustrate the within host survival mechanisms of Listeria monocytogenes. The simulator incorporates the gastric physiology and digestion processes that are critical for pathogen survival in the stomach. Mathematical formulations for the...
Sat, 07/11/2020 - 04:02
Juveniles are considered as one of the most vulnerable population groups concerning mycotoxins and their modified forms. The weaning stage is a particularly vulnerable period in the life of mammals, reflected in intestinal and immune dysfunction. The current study investigated the toxicokinetic (TK) characteristics of zearalenone (ZEN), zearalenone-14-glucoside (ZEN14G), and zearalenone-14-...
Sat, 07/11/2020 - 04:01
In Japan, strategies for ensuring food safety have been developed without reliable scientific evidence on the relation between foodborne infections and foods. The aim of this research was to provide information on the proportions of foodborne diseases caused by seven major causative pathogens ( Campylobacte r spp., Salmonella spp., EHEC, V. parahaemolyticus , Clostridium perfringens ,...
Sat, 07/11/2020 - 04:01
Human noroviruses are enteric pathogens causing a substantial proportion of acute gastroenteritis cases worldwide, irrespective of background variables such as age, ethnicity or gender. Although person-to-person contact is the general route of transmission, foodborne infections are also common. Thorough cooking eliminates noroviruses, but several food products such as berries, leafy vegetables or...
Sat, 07/11/2020 - 04:01
Preventing ill food employees from spreading pathogens to food and food contact surfaces remain an important objective of retail food safety policy in the United States. Since 2005, the U.S. Food and Drug Administration (FDA) has recommended food establishments implement employee health policies that include requirements for the exclusion or restriction of ill food employees and reporting, to the...
Sat, 07/11/2020 - 04:01
Vibrio parahaemolyticus and V. vulnificus are naturally occuring human pathogenic bacteria commonly found in estuarine environments where oysters are cultured. The use of triploid oysters has increased, due to their rapid growth rate and that they maintain a high quality throughout the year. Previous work suggested levels of Vibrio spp. may be lower in triploid oysters, as compared to diploids....
Sat, 07/11/2020 - 02:01
Impacts on urban water resources are invariably caused by the development of urban centers and the occupation of the watershed. The release of untreated effluents and urban runoff are sources of metals in adjacent water bodies. It is therefore important to conduct studies on the occurrence of these trace elements in the environment and the risks posed to human health. The aim of the present study...
Sat, 07/11/2020 - 02:01
Recent large-scale pandemics such as the covid19, H1N1, Swine flu, Ebola and the Nipah virus, which impacted human health and livelihoods, have come about due to inadequate food systems safeguards to detect, trace and eliminate threats arising from zoonotic diseases. Such diseases are transmitted to humans through their interaction with animals in the food value chain including through the...
Sat, 07/11/2020 - 02:01
Detection of norovirus (NoV) and hepatitis A virus (HAV) on fruits and vegetables using current standard methodologies can be inefficient. Method optimisation focussing on ease, rapidity and increased viral RNA recovery is needed for efficient reverse transcription (RT)-qPCR detection of viruses. A simple and quick direct lysis method for RNA extraction was optimised (method A) to achieve...
Sat, 07/11/2020 - 02:01
Abstract Background and aims Large areas of paddy fields have been contaminated by cadmium (Cd) in both China and worldwide, resulting in excessive Cd accumulation in rice grains. Here, we investigated the effects of cultivars, water regimes, and growth stages on Cd accumulation in rice with different radial oxygen loss (ROL). Methods Two groups of experiments were conducted: pot trials with...
Sat, 07/11/2020 - 00:00
In recent years, very many incidences of contamination with aflatoxin B1 (AFB1) in pistachio nuts have been reported as a major global problem for the crop. In Europe, legislation is in force and 12 μg/kg of AFB1 is the maximum limit set for pistachios to be subjected to physical treatment before human consumption. The goal of the current study was to develop a mechanistic, weather-driven...
Sat, 07/11/2020 - 00:00
International trade is highly affected by mycotoxin contaminations, which result in an annual 5% to 10% loss of global crop production [...]
Sat, 07/11/2020 - 00:00
The recurrence of Pseudomonas aeruginosa (PA) biofilm infections is a major issue in cystic fibrosis (CF) patients. A pivotal role is played by the presence of antibiotic-unresponsive persisters and/or viable but non-culturable (VBNC) forms, whose development might be favored by subinhibitory antibiotic concentrations. The involvement of tobramycin and ciprofloxacin, widely used to treat CF PA...
Fri, 07/10/2020 - 22:11
African swine fever (ASF) is a severe viral disease that affects both domestic and wild pigs and is responsible for major production and economic losses. As a transboundary animal disease (TAD) it can be spread by live or dead pigs and via pork products. Transmission can take place via contaminated feed and fomites including shoes, clothes, vehicles, knives and equipment. Unlike classical swine...
Fri, 07/10/2020 - 22:11
Food companies should comply with the requirements of a zero‐waste concept to adapt to the circular economy requirements. In fruit companies, usually seeds are discarded without proper utilization and extraction of the bioactive compounds. Fruit seeds are sources of chemical compounds that can be extracted, studied, and applied in high value‐added products. Thus, in this work the experimental...
Fri, 07/10/2020 - 22:11
In recent years, to increase growth rate and prevent infectious diseases, an excessive use of antibiotics in livestock breeding processes has resulted in the presence of antibiotic residues in animal foods. In this experiment, a new kind of electrochemical sensor is prepared based on magnetic mesoporous hollow carbon microspheres (MHM) as a penicillinase (Pen X) adsorption carrier to rapidly...
Fri, 07/10/2020 - 22:10
Foods rich in anthocyanins are thermally treated to ensure their safety and are stored for a period of time before consumption. Thermal pretreatment could enhance the color and stability of anthocyanins content in most food products. The combination of thermal treatment and storage under subsequent conditions had a significant effect on anthocyanins. The rose powder dispersed in water, aqueous...
Fri, 07/10/2020 - 22:10
Levetiracetam is an antiepileptic drug for the treatment of psychiatric patients. In this study, a selective, straightforward, and rapid online heart‐cutting LC method was developed for the therapeutic drug monitoring of levetiracetam. This method allows for the determination of levetiracetam in human plasma without complex sample preparation. The mobile phases consisted of 30 mM aq. ortho‐...
Fri, 07/10/2020 - 22:10
Drug resistance is one of the main problems of cancer treatment. For this reason, combination therapy is commonly used for years. The combination of a chemotherapeutic, carboplatin, and the epigenetic drug decitabine is a new approach to modulate drug resistance. Nanoparticulate systems can overcome the drawbacks associated with the drug combinations. An analytical method that can detect and...
Fri, 07/10/2020 - 22:07
ABSTRACT BACKGROUND Aspergillus flavus, a saprophytic fungus, is regularly detected in oil‐enriched seeds. During colonisation, this organism releases aflatoxins that pose a serious risk to food safety and human health. Therefore, an eco‐friendly biological approach to inhibit the pathogen is desirable. RESULTS Experimental results indicated that A. flavus spores could not germinate in potato...
Fri, 07/10/2020 - 18:02
Melatonin (Mel) is known to prevent and mitigate lead (Pb)-induced gonadotoxicity. However, there is no report in literature on the endogenous levels of different biomarkers after the cessation of Pb exposure, with or without treatment with Mel. Fifty adult male Wistar rats were divided into five groups (N = 10), which included control ((vehicle (normal saline) - treated) − 0.1 ml/day); lead...
Fri, 07/10/2020 - 16:00
Histophilus somni and Pasteurella multocida are two of multiple agents responsible for bovine respiratory disease (BRD) in cattle. Following respiratory infection of calves with H. somni, P. multocida may also be isolated from the lower respiratory tract. Because H. somni may form a biofilm during BRD, we sought to determine if P. multocida can co-exist with H. somni in a polymicrobial biofilm in...
Fri, 07/10/2020 - 16:00
Aliarcobacter cryaerophilus (formerly Arcobacter cryaerophilus) is a globally emerging foodborne and zoonotic pathogen. However, little is known about the species’ genomic features and diversity, antibiotic resistance and virulence. In this study, 27 A. cryaerophilus strains from water poultry in Thuringia, Germany, were investigated using whole-genome sequencing. Four of these strains were...
Fri, 07/10/2020 - 16:00
Bacteriophages are pivotal elements in the dissemination of virulence genes. The main virulence determinants of Shiga Toxin producing E. coli, Shiga Toxins (Stx), are encoded by genes localized in the genome of lambdoid bacteriophages. Stx comprise two antigenically different types, Stx1 and Stx2, further divided into subtypes. Among these, certain Stx2 subtypes appear to be more commonly...
Fri, 07/10/2020 - 16:00
Vibrio cholerae, the etiological agent of cholera, employs quorum sensing (QS) pathways to control the expression of virulence factors, including the production of cholera toxin and biofilm formation. Acquired antibiotic resistance in V. cholerae draws attention to the development of novel therapeutics that counteract virulence, rather than the viability of the pathogen. In this context, we...
Fri, 07/10/2020 - 16:00
Arbuscular mycorrhizal fungi (AMF) are known to improve the resistance of host plants against various heavy metal stresses. However, the arsenic (As) resistance mechanism of AMF-inoculated woody legumes remains unclear. In this study, black locust (Robinia pseudoacacia L.) seedlings were cultivated in potted soils inoculated with or without AMF Rhizoglomus intraradices under three different...
Fri, 07/10/2020 - 16:00
Several studies have recently identified the main factors contributing to the bacterial colonization of newborns and the dynamics of the infant microbiome development. However, most of these studies address large time periods of weeks or months after birth, thereby missing on important aspects of the early microbiome maturation, such as the acquisition of antibiotic resistance determinants during...
Fri, 07/10/2020 - 08:01
by Mihkel Mäesaar, Triin Tedersoo, Kadrin Meremäe, Mati Roasto The reservoir and source of human campylobacteriosis is primarily considered to be poultry, but also other such as ruminants, pets and environmental sources are related with infection burden. Multilocus sequence typing is often used for Campylobacter epidemiological studies to determine potential sources of human infections. The...
Fri, 07/10/2020 - 08:01
by Amanda L. Miller, J. Alex Pasternak, Nicole J. Medeiros, Lauren K. Nicastro, Sarah A. Tursi, Elizabeth G. Hansen, Ryan Krochak, Akosiererem S. Sokaribo, Keith D. MacKenzie, Melissa B. Palmer, Dakoda J. Herman, Nikole L. Watson, Yi Zhang, Heather L. Wilson, R. Paul Wilson, Aaron P. White, Çagla Tükel Reactive arthritis, an autoimmune disorder, occurs following gastrointestinal infection with...
Fri, 07/10/2020 - 08:01
by Mohammad O. Dahl Brucellosis is an endemic disease in food-producing animals in Mosul, Iraq. The objectives of the study reported here were: (i) to identify and assess the evidence and knowledge gaps in published studies that have examined brucellosis in different food-producing animals in Mosul, Iraq; using systematic review approach, and (ii) to quantify the seroprevalence of brucellosis in...
Fri, 07/10/2020 - 08:01
by Jawad Aarrouf, Laurent Urban Leaves of lettuce, pepper, tomato and grapevine plants grown in greenhouse conditions were exposed to UV-C light for either 60 s or 1 s, using a specific LEDs-based device, and wavelengths and energy were the same among different light treatments. Doses of UV-C light that both effectively stimulated plant defences and were innocuous were determined beforehand....
Fri, 07/10/2020 - 08:01
by Pierrot Derjany, Sirish Namilae, Dahai Liu, Ashok Srinivasan There is direct evidence for the spread of infectious diseases such as influenza, SARS, measles, and norovirus in locations where large groups of people gather at high densities e.g. theme parks, airports, etc. The mixing of susceptible and infectious individuals in these high people density man-made environments involves pedestrian...
Fri, 07/10/2020 - 08:01
by Bilal Kaaki, Digant Gupta Background Sacral neuromodulation (SNM) is a minimally invasive fully reversible therapy that was approved in 1997 for overactive bladder syndrome (OAB) refractory to behavior modification and pharmacotherapy. Despite being in use for over two decades, the data on medium to long-term safety and efficacy of SNM in OAB is limited. We investigated the medium-term...
Fri, 07/10/2020 - 06:09
Author(s): Oladipupo Odunayo Olatunde, Soottawat Benjakul, Kitiya Vongkamjan The influence of cold plasma (CP) generated using the mixed gases (oxygen, carbon dioxide argon: 10: 60:30) for 5 min in combination with ethanolic coconut husk extract (ECHE) in either free or liposomal encapsulated form (LE-ECHE) at a concentration of 400 ppm on shelf-life of refrigerated Asian sea bass slices (ASBS)...
Fri, 07/10/2020 - 06:09
Author(s): Yiwen Bao, Lavanya Reddivari, Jen-Yi Huang In this study, high voltage atmospheric cold plasma (HVACP) with different working gases (air, Ar, He and N2) was used to modify the surface of tomato pomace, aiming to facilitate the migration of phenolic compounds during extraction hence increase their extraction efficiency. In addition to rupturing the epidermal cells of tomato pomace,...
Fri, 07/10/2020 - 06:09
Author(s): Verger Philippe, Agamy Neveen, Anshasi Marwa, Al-Yousfi Ahmad Basel Fruits and vegetables represent both a considerable contribution to a healthy dietary pattern of the population and a source of income for countries exporting part of their production. Countries of the Eastern Mediterranean Region (EMR) have undergone rapid urbanization and changes in lifestyle and consumer demands....
Fri, 07/10/2020 - 06:06
Author(s): Ana Juan-García, Marie-Abèle Bind, Florian Engert The presence of mycotoxins in food has created concern. Mycotoxin prevalence in our environment has changed in the last few years maybe due to climatic and other environmental changes. Evidence has emerged from in vitro and in vivo models: some mycotoxins have been found to be potentially carcinogenic, embryogenically harmful,...
Fri, 07/10/2020 - 06:06
LWT
Author(s): Seung-Hae Gwak, Jin-Hee Kim, Se-Wook Oh It is difficult to detect a small amount of pathogens present in ready-to-eat foods without enriching it. Although enrichment is needed to increase the bacterial population, the time required for this impedes the rapid detection of pathogens. This study was designed to detect Escherichia coli O157:H7 and Salmonella Typhimurium more quickly and...
Fri, 07/10/2020 - 04:02
Human African trypanosomiasis is a neglected tropical disease caused by Trypanosoma brucei parasites. These protists are unable to produce the purine ring, making them vulnerable to the effects of purine nucleoside analogues. Starting from 3′-deoxytubercidin (5), a lead compound with activity against central-nervous-stage human African trypanosomiasis, we investigate the structure–activity...
Fri, 07/10/2020 - 04:02
As one of the main causes of bacterial diarrhea and a major risk factor for triggering Guillain–Barré autoimmune syndrome, campylobacteriosis, that is, Campylobacter spp. infections, represents a major health issue worldwide. There is thus a pressing need for developing an effective and broad-coverage campylobacteriosis vaccine. Campylobacter jejuni, an encapsulated, multidrug resistant Gram-...
Fri, 07/10/2020 - 02:01
The objectives of this study was to diagnose Cd and Pb contamination in soil and to identify the main factors that contribute to the transfer of these elements to tomato plants and fruits and contamination levels of the fruits in tropical mountain conditions. Contamination of the study area soils by Cd and Pb was verified. This contamination stemmed from the intensive use of agricultural inputs,...
Fri, 07/10/2020 - 02:01
Peptide nucleic acids (PNAs) are DNA/RNA analogs in which sugar-phosphate backbone is replaced by N-2-aminoethylglycine repeating units. Since PNA contains a neutral skeleton, there is no electrostatic repulsion, resulting in significant stability of its hybrid structure with complementary oligonucleotides. At present, PNA has taken the place of DNA probe in many studies. There are several...
Fri, 07/10/2020 - 02:01
The contaminated Kaynaklar soil containing high level of diesel (100,000 mg/kg dw) was treated in slurry systems with solid-to-liquid ratios (S/L) of 1/5, 1/10, and 1/20 to describe the performance of physical treatment. The soil microbial mass was inhibited by using mercury chloride and autoclaving prior to the diesel spiking in order to eliminate any bacterial degradation of non-aqueous phase...
Thu, 07/09/2020 - 22:11
In order to control Highly Pathogenic Avian Influenza (HPAI) H5N1 and Low Pathogenic Avian Influenza (LPAI) H9N2 virus spread in endemically infected countries, a detailed understanding of infection patterns is required. We conducted cross‐sectional studies in Bangladesh in 2016 and 2017, on 144 backyard, 106 broiler and 113 layer chicken farms. Although all sampled birds were negative for H5...
Thu, 07/09/2020 - 22:11
Environmental testing of poultry premises after an outbreak of an infectious disease like avian influenza (AI) or Newcastle disease, is essential to promptly verify virus‐free status and subsequently return to normal operations. In an attempt to establish an optimized sampling protocol a laboratory study simulating an AI virus contaminated poultry house with wire layer cages was conducted. Three...
Thu, 07/09/2020 - 16:00
In the present work, we used a double cell screening approach based on phenanthrene (phe) epifluorescence histochemical localization and oxygen radical detection to generate new data about how some specialized cells are involved in tolerance to organic xenobiotics. Thereby, we bring new insights about phe [a common Polycyclic Aromatic Hydrocarbon (PAH)] cell specific detoxification, in two...
Thu, 07/09/2020 - 16:00
Mycobacterium tuberculosis (Mtb) infects macrophages and macrophage-derived foam cells, a hallmark of granulomata in tuberculous lesions. We analyzed the effects of lipid accumulation in human primary macrophages and quantified strong triglyceride and phospholipid remodeling which depended on the dietary fatty acid used for the assay. The enrichment of >70% in triglyceride and phospholipids...
Thu, 07/09/2020 - 16:00
Staphylococcal infection is one of the most pressing problems in modern medicine due to the increasing antibiotic resistance with the overuse of antibiotics. Conventional methods for identification and antimicrobial susceptibility testing (AST) generally take 3–7 days and require skilled technicians. In this study, a microfluidic device based on loop-mediated isothermal amplification (LAMP) was...
Thu, 07/09/2020 - 14:04
In this study Aflatoxin B1 (AFB1), ochratoxin A (OTA) and zearalenone (ZEN) occurrence in fish feed, regarding its chemical composition, were investigated. Besides, AFB1 bioaccessibility to fish was evaluated by in vitro digestion. Mycotoxins were extracted by QuEChERS and quantified by HPLC-FLD. Results showed that 93.3% of the samples were contaminated at maximum levels of 16.5, 31.6, and 322...

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